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This lecture delves into the innovative field of organ chip technology, focusing on tissue engineering, micro-nanofabrication, and regenerative medicine applications. The instructor discusses the development of bio-inspired solutions for creating tissues and organs, emphasizing the importance of regulating the cellular environment. Various techniques such as microfluidics, microfibers, and bioprinting are explored to assemble small parts into functional tissues. The lecture also covers the integration of sensors into organ structures to monitor the physical and chemical environment, enabling real-time analysis and drug testing on organ-on-chip platforms.