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This lecture covers the neural control of movement, focusing on the sensorimotor systems involving the spinal cord, cerebellum, and brainstem. It explains the role of upper motor neurons, motor cortex, basal ganglia, and cerebellum in planning and executing voluntary movements. The lecture also delves into the organization of motor neuron pools in the spinal cord and the coordination of ongoing movements. Additionally, it discusses the somatosensory feedback loop and the spinal cord circuitry underlying muscle stretch reflexes. The presentation concludes with insights into studying motor neurons using transgenic mice and induced pluripotent stem cells for neuroanatomy research.