Nanoplasmonics for Disease Detection

This lecture discusses the use of localized surface plasmon resonance (LSPR) for detecting bacteria, DNAs, and biomarkers related to diseases. The speaker explains the advantages of LSPR over electrochemical measurements, the importance of collaboration with chemists to develop specific chemistry for target analytes, and the potential of engineered proteins like soma-mers for binding kinetics. The lecture also covers the sensitivity and selectivity of nanoplasmonics, the portability of the detection system, and the cost-effectiveness of the instrument. The speaker presents a case study of a spectrometer technology developed in collaboration with Hamamatsu, highlighting its unique scattering properties and digital processing for material identification.