Microtubules: Structure and Regulation

In course

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Description

This lecture covers the structure and regulation of microtubules, focusing on the dynamic polymers of tubulin dimers, the role of GTP hydrolysis, nucleation, and the assembly process. It also discusses the functions of y-tubulin, MTOC, and accessory proteins in microtubule organization. The instructor highlights the mechanisms of catastrophe and rescue, as well as the impact of various proteins like stathmin, XMAP215, and kinesin-13 on microtubule dynamics.

Instructor

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Official source

https://mediaspace.epfl.ch/media/0_z5fvbd98

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