Person
Alizée Jéléna Grimm
This person is no longer with EPFL
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Related publications (6)
Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.
Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
George Coukos, Julien Dorier, Christian Iseli, Mauro Delorenzi, Alizée Jéléna Grimm, Giovanni Ciriello, Alexandre Harari, Marco Mina
In this study, we investigate mechanisms leading to inflammation and immunoreactivity in ovarian tumors with homologous recombination deficiency (HRD). BRCA1 loss is found to lead to transcriptional reprogramming in tumor cells and cell-intrinsic inflammat ...
2021Mechanisms of tolerance induction by erythrocyte-targeted antigens
Immune-mediated disorders such as autoimmune diseases, graft-versus-host disease or allergies, are a major contemporary burden. Despite significant advances in the field of immunological tolerance, immunosuppressive drugs are still the current hallmark for ...
EPFL2016Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses
Eleonora Simeoni, Jeffrey Alan Hubbell, Melody Swartz, Alexandre de Titta, Alizée Jéléna Grimm, Ziad Julier
Subunit vaccines, employing purified protein antigens rather than intact pathogens, require the addition of adjuvants for enhanced immunogenicity with a correct balance between strong activation of the immune system and low toxicity. Here we show that the ...
Elsevier Sci Ltd2016