Person

Aleksandre Japaridze

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Related publications (12)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Structural and DNA binding properties of mycobacterial integration host factor mIHF

Stewart Cole, David Lyndon Emsley, Giovanni Dietler, Luciano Andres Abriata, Nina Theres Odermatt, Moreno Lelli, Jérémie Piton, Aleksandre Japaridze, Rajkumar Singh

In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct transcriptional control. Mycobacterial integration host factor (mIHF, rv1388) is a NAP restricted ...
2020

Spatial confinement induces hairpins in nicked circular DNA

Giovanni Dietler, Aleksandre Japaridze, Enzo Orlandini

In living cells, DNA is highly confined in space with the help of condensing agents, DNA binding proteins and high levels of supercoiling. Due to challenges associated with experimentally studying DNA under confinement, little is known about the impact of ...
Oxford University Press (OUP)2017

Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein

Giovanni Dietler, Aleksandre Japaridze, Sylvain Renevey

Structural differentiation of bacterial chromatin depends on cooperative binding of abundant nucleoid-associated proteins at numerous genomic DNA sites and stabilization of distinct long-range nucleoprotein structures. Histone-like nucleoid-structuring pro ...
American Society for Biochemistry & Molecular Biology (ASBMB)2017
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