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Publication
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A one-pot, 5-component, domino process was used to prep. 7 hexasubstituted benzenes, e.g., I, in 32-67% yield. The 5 components for I were BuNH2, heptanal, isocyanide II, PhC==CCO2C6F5, and N-phenylmaleimide. The process creates 7 chem. bonds and delivers 5 elements of diversity into the compact polyheterocycle. [on SciFinder (R)]