The water soluble tris-aqua complex Gd(dhqN-SO3)(H2O)(3) based on a hexadentate hydroxyquinoline ligand shows high thermodynamic stability and high relaxivity (12.54 mM(-1) s(-1) at 1.2 T). Its non-covalent confinement in 25 nm silica nanoparticles prevents transmetallation and endogenous anion binding and leads to higher relaxivity over a wide range of magnetic fields.
Ardemis Anoush Boghossian, Giulia Tagliabue, Sayyed Hashem Sajjadi, Alessandra Antonucci, Shang-Jung Wu, Theodoros Tsoulos, Amirmostafa Amirjani
Francesco Stellacci, Zekiye Pelin Güven, Giulia Rossi