Methods for functionalising polymers for tissue engineering are disclosed in which a polymer matrix is activated to bind to biological materials such as cells by covalently bonding a hydrophilic polymer to carboxy groups of a polymer matrix. The hydrophilic polymer comprises a ligand group or ligand group precursor which can bind to an extracellular matrix protein, thereby allowing cells to adhere and proliferate on the polymer matrix.
Vassily Hatzimanikatis, Liliana Angeles Martinez
Ardemis Anoush Boghossian, Melania Reggente, Fabian Fischer