A provitamin is a substance that may be converted within the body to a vitamin. The term previtamin is a synonym.
The term "provitamin" is used when it is desirable to label a substance with little or no vitamin activity, but which can be converted to an active form by normal metabolic processes.
Some provitamins are:
"Provitamin A" is a name for β-carotene, which has only about 1/6 the biological activity of retinol (vitamin A); the body uses an enzyme to convert β-carotene to retinol. In other contexts, both β-carotene and retinol are simply considered to be different forms (vitamers) of vitamin A.
"Provitamin B5" is a name for panthenol, which may be converted in the body to vitamin B5 (pantothenic acid).
Menadione is a synthetic provitamin of vitamin K.
Provitamin D2 is ergosterol, and provitamin D3 is 7-dehydrocholesterol. They are converted by UV light into vitamin D. The human body produces provitamin D3 naturally; deficiency is usually caused by a lack of sun exposure, not a lack of the provitamin.
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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects. In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). The major natural source of the vitamin is synthesis of cholecalciferol in the lower layers of epidermis of the skin, through a photo-chemical reaction of UVB light, from the sun exposure (specifically UVB radiation) or UVB lamps.
Hypervitaminosis A refers to the toxic effects of ingesting too much preformed vitamin A (retinyl esters, retinol, and retinal). Symptoms arise as a result of altered bone metabolism and altered metabolism of other fat-soluble vitamins. Hypervitaminosis A is believed to have occurred in early humans, and the problem has persisted throughout human history. Toxicity results from ingesting too much preformed vitamin A from foods (such as fish liver or animal liver), supplements, or prescription medications and can be prevented by ingesting no more than the recommended daily amount.
Retinol, also called vitamin A1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and reproductive development. Dietary sources include fish, dairy products, and meat. As a supplement it is used to treat and prevent vitamin A deficiency, especially that which results in xerophthalmia. It is taken by mouth or by injection into a muscle.
An amperometric method was applied for real-time monitoring of intracellular redox enzyme activity. Baker's yeast (Saccharomyces cerevisiae) cells were immobilized on platinum microband electrodes and mediated anodic currents were measured. The currents we ...
Successive treatment of 7-dehydrocholesterol (I) with Me3SiCH2K in THF, dry ice, mineral acid, and diazomethane gives a regioisomerically pure, homoconjugated ester II as a diastereomeric mixt., the minor component of which is thermodynamically more stable ...