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Successive treatment of 7-dehydrocholesterol (I) with Me3SiCH2K in THF, dry ice, mineral acid, and diazomethane gives a regioisomerically pure, homoconjugated ester II as a diastereomeric mixt., the minor component of which is thermodynamically more stable than the conjugated isomer III. [on SciFinder (R)]
François Maréchal, Jürg Alexander Schiffmann, Ivan Daniel Kantor, Ansgar Weickgenannt
Nicola Marzari, Tommaso Chiarotti, Andrea Ferretti
Aleksandra Radenovic, Mukeshchand Thakur, Andrey Chernev, Vasily Artemov, Lucie Navratilova, Nianduo Cai, Yunfei Teng, Tzu-Heng Chen