Fluoride therapy is the use of fluoride for medical purposes. Fluoride supplements are recommended to prevent tooth decay in children older than six months in areas where the drinking water is low in fluoride. It is typically used as a liquid, pill, or paste by mouth. Fluoride has also been used to treat a number of bone diseases.
Relatively high ingestion of fluoride by babies and children may result in white marks on the teeth known as fluorosis. Excessive ingestion by babies and children can also result in severe dental fluorosis, indicated by a brown or yellow coloring and weakness/brittleness of the teeth, or in severe cases, acute toxicity. Fluoride therapy typically uses the sodium fluoride form, though stannous fluoride may also be used. Fluoride decreases breakdown of teeth by acids, promotes remineralisation, and decreases the activity of bacteria. It is believed to work primarily through direct contact with the teeth in the mouth after they have emerged from the gums.
Fluoride came into use to prevent tooth decay in the 1940s. Fluoride is on the World Health Organization's List of Essential Medicines. In 2020, it was the 265th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Fluoride therapy has been proven to have a beneficial effect on the prevention of dental caries. Robust evidence supports the use of fluoride toothpaste (with concentrations of 1000 ppm and above) to reduce the risk of dental caries in school-aged children and adolescents. The ingestion of fluoride as primary teeth are being developed has shown that the teeth have formed stronger and more resistant for caries, though increases the risk of dental fluorosis. Water and milk fluoridation are two forms of systemic fluoride therapy that have been demonstrated to be effective at preventing dental cavities.
Fluoride supplementation has been extensively studied for the treatment of postmenopausal osteoporosis. This supplementation does not appear to be effective; even though sodium fluoride increases bone density, it does not decrease the risk of fractures.
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Fluoride toxicity is a condition in which there are elevated levels of the fluoride ion in the body. Although fluoride is safe for dental health at low concentrations, sustained consumption of large amounts of soluble fluoride salts is dangerous. Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.
Oral hygiene is the practice of keeping one's oral cavity clean and free of disease and other problems (e.g. bad breath) by regular brushing of the teeth (dental hygiene) and adopting good hygiene habits. It is important that oral hygiene be carried out on a regular basis to enable prevention of dental disease and bad breath. The most common types of dental disease are tooth decay (cavities, dental caries) and gum diseases, including gingivitis, and periodontitis.
Water fluoridation is the controlled adjustment of fluoride to a public water supply solely to reduce tooth decay. Fluoridated water contains fluoride at a level that is effective for preventing cavities; this can occur naturally or by adding fluoride. Fluoridated water operates on tooth surfaces: in the mouth, it creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes and increases the rate at which it remineralizes in the early stages of cavities.
If polymer electrolyte water electrolysis (PEWE) is to penetrate the energy market in the context of power-to-x, challenges related to component durability need to be understood and addressed. In this study, PEWE component degradation mechanisms are induce ...
2020
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Densely substituted fused aromatic triazenes can be prepared by [2 + 2 + 2] cyclotrimerization reactions of 1-alkynyl triazenes. The Cp*Ru-catalyzed cyclization proceeds well with both simple alkynyl triazenes and tethered 1-diynyl triazenes. Attractively, ...
2019
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Prolonged consumption of water contaminated with fluoride ions (F-) at concentrations exceeding 1.5 ppm can lead to considerable health implications, particularly in children and developing embryos. With irreversible and potentially severe forms of fluorid ...