The American chestnut (Castanea dentata) is a large, fast-growing deciduous tree of the beech family native to eastern North America. As is true of all species in genus Castanea, the American chestnut produces burred fruit with edible nuts. The American chestnut was one of the most important forest trees throughout its range.
During the early to mid 20th century, American chestnut trees were devastated by chestnut blight, a fungal disease that came from Chinese chestnut trees that were introduced into North America from East Asia. It is estimated that the blight killed between 3 and 4 billion American chestnut trees in the first half of the 20th century, beginning in 1904. Very few mature specimens of the tree exist within its historical range, although many small shoots of the former live trees remain. There are hundreds of large (2 to 5 ft diameter) American chestnuts outside its historical range, some in areas where less virulent strains of the pathogen are more common, such as the 600 to 800 large trees in Northern Michigan. The species is listed as endangered in the United States and Canada. American chestnuts are also susceptible to ink disease, particularly in the southern part of its native range; this likely contributed to the devastation of the species.
Several groups are attempting to create blight-resistant American chestnuts. Scientists at the SUNY College of Environmental Science and Forestry created the Darling 58 cultivar of American chestnut by inserting the oxalate oxidase gene from wheat into the genome of an American chestnut. When expressed in the vascular cambium of the Darling 58 cultivar, the oxalate oxidase enzyme degrades the oxalic acid produced by the chestnut blight, reducing damage to the vascular cambium and resisting girdling of the trunk. As of 2021, the researchers who developed this cultivar are working toward applying for government permission to make these trees available to the public. If approved, these chestnut trees would be the first genetically modified forest trees released into the wild in the United States.
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Appalachia (ˌæpəˈlætʃə,-leɪtʃə,-leɪʃə) is a socio-economic region located in the central and southern sections of the Appalachian Mountains of the Eastern United States. It stretches from the western Catskill Mountains in the east end of the Southern Tier of New York state west and south into Pennsylvania, continuing on through the Blue Ridge Mountains into northern Georgia, and through the Great Smoky Mountains from North Carolina into Tennessee and northern Alabama. In 2020, the region was home to an estimated 26.
The chestnuts are the deciduous trees and shrubs in the genus Castanea, in the beech family Fagaceae. They are native to temperate regions of the Northern Hemisphere. The name also refers to the edible nuts they produce. The unrelated horse chestnuts (genus Aesculus) are not true chestnuts, but are named for producing nuts of similar appearance that are mildly poisonous to humans. True chestnuts should also not be confused with water chestnuts, which are tubers of an aquatic herbaceous plant in the sedge family Cyperaceae.
New York, often called New York City or NYC, is the most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is the most densely populated major city in the United States. The city is more than twice as populous as Los Angeles, the nation's second-largest city. New York City is situated at the southern tip of New York State. Situated on one of the world's largest natural harbors, New York City comprises five boroughs, each of which is coextensive with a respective county.