Indo-Scythians (also called Indo-Sakas) were a group of nomadic Iranian peoples of Scythian origin who migrated from Central Asia southward into the northwestern Indian subcontinent, precisely into the modern-day South Asian regions of Afghanistan, Pakistan and northern India. The migrations persisted from the middle of the 2nd century BCE to the 4th century CE.
The first Saka king of India was Maues/Moga (1st century BCE) who established Saka power in Gandhara, Indus Valley, and other regions in today's Afghanistan, Pakistan and North India. The Indo-Scythians extended their supremacy over north-western subcontinent, conquering the Indo-Greeks and other local kingdoms. The Indo-Scythians were apparently subjugated by the Kushan Empire, by either Kujula Kadphises or Kanishka. Yet the Saka continued to govern as satrapies, forming the Northern Satraps and Western Satraps. The power of the Saka rulers started to decline in the 2nd century CE after the Indo-Scythians were defeated by the Satavahana emperor Gautamiputra Satakarni. Indo-Scythian rule in the northwestern subcontinent ceased when the last Western Satrap Rudrasimha III was defeated by the Gupta emperor Chandragupta II in 395 CE.
The invasion of northern regions of the Indian subcontinent by Scythian tribes from Central Asia, often referred to as the Indo-Scythian invasion, played a significant part in the history of the subcontinent as well as of nearby regions. In fact, the Indo-Scythian war is just one chapter in the events triggered by the nomadic flight of Central Asians from conflict with tribes such as the Xiongnu in the 2nd century CE, which had lasting effects on Bactria, Kabul, and the Indian subcontinent as well as far-off Rome in the west, and more nearby to the west in Parthia.
Ancient Roman historians, including Arrian and Claudius Ptolemy, have mentioned that the ancient Sakas ("Sakai") were nomadic people.
The first rulers of the Indo-Scythian Kingdom were Maues, c. 85–60 BCE, and Vonones, c. 75–65 BCE.
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The Western Satraps, or Western Kshatrapas (Brahmi:, Mahakṣatrapa, "Great Satraps") were Indo-Scythian (Saka) rulers of the western and central parts of India (extending from Saurashtra in the south and Malwa in the east, covering modern-day Sindh, Gujarat, Maharashtra, Rajasthan and Madhya Pradesh states), between 35 and 415 CE. The Western Satraps were contemporaneous with the Kushans who ruled the northern part of the Indian subcontinent, and were possibly vassals of the Kushans.
The Indo-Greek Kingdom, or Graeco-Indian Kingdom, also known historically as the Yavana Kingdom (Yavanarajya), was a Hellenistic-era Greek kingdom covering various parts of modern-day Afghanistan, Pakistan and northwestern India. This kingdom was in existence from 200 BC to the beginning of the common era. During its existence the kingdom was ruled over by 30 successive kings. Menander I, being the most well known amongst the Indo-Greek kings, is often referred to simply as "Menander," despite the fact that there was indeed another Indo-Greek King known as Menander II.
The Indo-Parthian Kingdom was a Parthian kingdom founded by Gondophares, and active from 19 CE to c. 226 CE. At their zenith, they ruled an area covering parts of eastern Iran, various parts of Afghanistan and the northwest regions of the Indian subcontinent (most of modern Pakistan and parts of northwestern India). The rulers may have been members of the House of Suren, and the kingdom has even been called the "Suren Kingdom" by some authors.
It is generally agreed that the hepatotoxic microcystins (MCs) are the most abundant toxins produced by cyanobacteria in freshwater. In various freshwater lakes in East Africa MC-producing Microcystis has been reported to dominate the phytoplankton, howeve ...