MycMyc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc. In cancer, c-myc is often constitutively (persistently) expressed. This leads to the increased expression of many genes, some of which are involved in cell proliferation, contributing to the formation of cancer.
Disengagement theoryThe disengagement theory of ageing states that "aging is an inevitable, mutual withdrawal or disengagement, resulting in decreased interaction between the aging person and others in the social system he belongs to". The theory claims that it is natural and acceptable for older adults to withdraw from society. There are multiple variations on disengagement theory, such as moral disengagement. Disengagement theory was formulated by Cumming and Henry in 1961 in the book Growing Old and was the first theory of aging that social scientists developed.
CoffinA coffin is a funerary box used for viewing or keeping a corpse, either for burial or cremation. Coffins are sometimes referred to as a casket, particularly in American English. Any box in which the dead are buried is a coffin, and while a casket was originally regarded as a box for jewelry, use of the word "casket" in this sense began as a euphemism introduced by the undertaker's trade.
Homologous recombinationHomologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded nucleic acids (usually DNA as in cellular organisms but may be also RNA in viruses). Homologous recombination is widely used by cells to accurately repair harmful DNA breaks that occur on both strands of DNA, known as double-strand breaks (DSB), in a process called homologous recombinational repair (HRR).
Life expectancyLife expectancy is a statistical measure of the estimate of the span of a life. The most commonly used measure is life expectancy at birth (LEB), which can be defined in two ways. Cohort LEB is the mean length of life of a birth cohort (in this case, all individuals born in a given year) and can be computed only for cohorts born so long ago that all their members have died. Period LEB is the mean length of life of a hypothetical cohort assumed to be exposed, from birth through death, to the mortality rates observed at a given year.
ImmortalityImmortality is the concept of eternal life. Some modern species may possess biological immortality. Some scientists, futurists, and philosophers have theorized about the immortality of the human body, with some suggesting that human immortality may be achievable in the first few decades of the 21st century with the help of certain technologies such as mind uploading (digital immortality). Other advocates believe that life extension is a more achievable goal in the short term, with immortality awaiting further research breakthroughs.
FuneralA funeral is a ceremony connected with the final disposition of a corpse, such as a burial or cremation, with the attendant observances. Funerary customs comprise the complex of beliefs and practices used by a culture to remember and respect the dead, from interment, to various monuments, prayers, and rituals undertaken in their honor. Customs vary between cultures and religious groups. Funerals have both normative and legal components.
