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Proprotein Convertases (PCs) constitute a family of serine proteases that activate various
hormones, growth factors and cell adhesion molecules by mediating endoproteolytic cleavage
of their secreted inactive precursors during their transit in the secret ...
Fully controllable autonomous vehicles offer unprecedented opportunities to address the inefficiency associated with selfish routing, a fundamental issue in transportation network modeling. This study proposes a route control scheme that aims to strike a b ...
Modern software systems heavily use the memory heap. As systems grow more complex and compute with increasing amounts of data, it can be difficult for developers to understand how their programs actually use the bytes that they allocate on the heap and whe ...
Humans are comparison machines: comparing and choosing an item among a set of alternatives (such as objects or concepts) is arguably one of the most natural ways for us to express our preferences and opinions. In many applications, the analysis of data con ...
Many modern services need to routinely perform tasks on a large scale. This prompts us to consider the following question:How can we design efficient algorithms for large-scale computation?In this thesis, we focus on devising a general strategy to addr ...
We propose a new proximal path-following framework for a class of constrained convex problems. We consider settings where the nonlinear-and possibly nonsmooth-objective part is endowed with a proximity operator, and the constraint set is equipped with a se ...
For over a decade now we have been witnessing the success of massive parallel computation (MPC) frameworks, such as MapReduce, Hadoop, Dryad, or Spark. One of the reasons for their success is the fact that these frameworks are able to accurately capture th ...
Clustering is a method for discovering structure in data, widely used across many scientific disciplines. The two main clustering problems this dissertation considers are K-means and K-medoids. These are NP-hard problems in the number of samples and cluste ...
Modern software systems heavily use the memory heap. As systems grow more complex and compute with increasing amounts of data, it can be difficult for developers to understand how their programs actually use the bytes that they allocate on the heap and whe ...
