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A benchmark dataset for machine learning in ecotoxicology

Kristin Schirmer, Marco Baity-Jesi, Fernando Perez Cruz

The use of machine learning for predicting ecotoxicological outcomes is promising, but underutilized. The curation of data with informative features requires both expertise in machine learning as well as a strong biological and ecotoxicological background, ...

Nature Portfolio2023

Morphology of Nanostructured Tantalum Oxide Controls Stem Cell Differentiation and Improves Corrosion Behavior

Ece Uslu

Tantalum is receiving increasing attention in the biomedical field due to its biocompatible nature and superior mechanical properties. However, the bioinert nature of tantalum still poses a challenge and limits its integration into the bone tissue. To addr ...

Amer Chemical Soc2023

Biological material pooling device for biological or biomolecule purification

Bart Deplancke, Riccardo Dainese, Daniel Alpern

The present invention concerns a biological material pooling device for biological or biomolecule purification comprising a receptacle including a first orifice comprising ordefining a rectangular opening, the receptacle being configured to receive at leas ...

2023

A study model for reconstructing urban ecological niches

Francesco Mondada, Robert Matthew Mills

The Living Arch is a study model that was designed to showcase our ongoing research into bioactive architectural systems to be inhabited by honeybees. The arch is a synergistic combination of 3D printing and active mycelia growth, created for a museum exhi ...

CRC Press2022

Monodisperse Selectively Permeable Hydrogel Capsules Made from Single Emulsion Drops

Esther Amstad, Alexandre Louis André Persat, Huachuan Du, Mathias Steinacher, Alice Cont

Capsules are often used to protect chemical and biological entities from the environment, to control the timing and location of their release, or to facilitate the collection of waste. Their performance depends on the thickness and composition of their she ...

2021

Building biosecurity for synthetic biology

Marie-Valentine Renée Agnès Florin

The fast-paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen-oriented security, recombinantDNAresearch, and broa ...

2020

Robust Distributed Learning

El Mahdi El Mhamdi

Whether it occurs in artificial or biological substrates, {\it learning} is a {distributed} phenomenon in at least two aspects. First, meaningful data and experiences are rarely found in one location, hence {\it learners} have a strong incentive to work t ...

EPFL2020

A fish intestinal barrier model to assess the interaction with chemicals in vitro

Hannah Inka Schug

The intestinal epithelium acts as vital gate keeper between the fish and its surrounding environment. A single layer of connected epithelial cells forms a selective barrier, which, among other essential functions, is important for nutrient uptake and defen ...

EPFL2019

TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

Kristin Schirmer, Hannah Inka Schug

Transfer of compounds across cellular barriers is a critical step of compound uptake into organisms. Using in vitro barrier systems to evaluate such transfer is attractive because of the higher throughput and reduced resource needs compared to animal studi ...

ROYAL SOC CHEMISTRY2018

Quantitative chemical biosensing by bacterial chemotaxis in microfluidic chips

Harald Van Lintel, Jan Roelof van der Meer, Clémence Roggo

Whole-cell bacterial bioreporters are proposed asalternatives to chemical analysis of, for example, pol-lutants in environmental compartments. Commonlybased on reporter gene induction, bioreporters pro-duce a detectable signal within 30 min to a few hoursa ...

2018

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TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

Kristin Schirmer, Hannah Inka Schug

ROYAL SOC CHEMISTRY2018