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Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

Hubert van den Bergh, Patrycja Nowak-Sliwinska

Photodynamic therapy (PDT) induces damage to the endothelium, which can lead to increased vascular permeability and, under intensive PDT conditions, even to platelet aggregation, vasoconstriction, and blood flow stasis. Eventually, ischemia, hypoxia, and i ...

Springer Netherlands2010

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

Stephane Kontos, Jeffrey Alan Hubbell

Poor pharmacokinetic profiles are often the underlying reason for the failure of novel protein drugs to reach clinical translation. Current passive half-life improvement methods focus on increasing the apparent hydrodynamic radius of the drug. We sought to ...

American Chemical Society2010

P450-mediated electrochemical sensing of drugs in human plasma for personalized therapy

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini

Nowadays, the concept of personalized therapy gains momentum. Pharmacogenomics, which represents a first answer to these needs, has the drawback of neglecting some variations of therapy response due to non-genetic factors. The aim of this paper is to inves ...

2010

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, James Brandon Dixon, Dimana Miteva

RATIONALE: Lymphatic transport of peripheral interstitial fluid and dendritic cells (DCs) is important for both adaptive immunity and maintenance of tolerance to self-antigens. Lymphatic drainage can change rapidly and dramatically on tissue injury or infl ...

American Heart Association2010

Three-dimensional morphometry of strained bovine periodontal ligament using synchrotron radiation-based tomography

John Botsis, Joël Cugnoni, Marzio Bergomi, Marco Stampanoni, Philipp Schneider

The periodontal ligament (PDL) is a highly vascularized soft connective tissue. Previous studies suggest that the viscous component of the mechanical response may be explained by the deformation-induced collapse and expansion of internal voids (i.e. chiefl ...

2010

Effects of morphogen advection on osteogenic differentiation of hMSCs using a microfluidic device with 2D micro patterned cell colonies

Dominique Pioletti, Alexandre Terrier, Miguel Gortchacow

It has been established that primary stability of femoral stems is a determinant of the clinical success of cementless total hip arthroplasty. Excessive interface micromotions may lead to a peri-implant fibrous tissue formation resulting in aseptic looseni ...

2010

Role of lymphatic vessels in tumor immunity: passive conduits or active participants?

Melody Swartz, Amanda Waite Lund

Research in lymphatic biology and cancer immunology may soon intersect as emerging evidence implicates the lymphatics in the progression of chronic inflammation and autoimmunity as well as in tumor metastasis and immune escape. Like the blood vasculature, ...

Springer Verlag2010

Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals

Jacques Fellay, Patrick Descombes, Amalio Telenti

There is great interindividual variability in HIV-1 viral setpoint after seroconversion, some of which is known to be due to genetic differences among infected individuals. Here, our focus is on determining, genome-wide, the contribution of variable gene e ...

2010

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Blood

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

P450-mediated electrochemical sensing of drugs in human plasma for personalized therapy

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

Three-dimensional morphometry of strained bovine periodontal ligament using synchrotron radiation-based tomography

Lymphatic Biodistribution of Polylactide Nanoparticles

Effects of morphogen advection on osteogenic differentiation of hMSCs using a microfluidic device with 2D micro patterned cell colonies

Construction of a high order fluid-structure interaction solver

Role of lymphatic vessels in tumor immunity: passive conduits or active participants?

Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals

Graph Chatbot

Chat with Graph Search

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

P450-mediated electrochemical sensing of drugs in human plasma for personalized therapy

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

Role of lymphatic vessels in tumor immunity: passive conduits or active participants?

Three-dimensional morphometry of strained bovine periodontal ligament using synchrotron radiation-based tomography

Effects of morphogen advection on osteogenic differentiation of hMSCs using a microfluidic device with 2D micro patterned cell colonies

Construction of a high order fluid-structure interaction solver

Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals

Lymphatic Biodistribution of Polylactide Nanoparticles