Concept

Potassium channel

Related publications (385)

On Codes Decoding a Constant Fraction of Errors on the BSC

We strengthen the results from a recent work by the second author, achieving bounds on the weight distribution of binary linear codes that are successful under block-MAP (as well as bit-MAP) decoding on the BEC. We conclude that a linear code that is succe ...

ASSOC COMPUTING MACHINERY2021

The role of metal ions in G protein-coupled receptor signalling and drug discovery

Horst Vogel, Shuguang Yuan, Xueying Wang

Metal ions, such as Na+, Mg2+, Ca2+, and Zn2+, are highly abundant in biological systems. For many G protein-coupled receptors (GPCRs), metal ions, especially Na+, have been found to stabilize the receptors' inactivate state preventing receptor activation. ...

WILEY2021

Field-to-Transmission Line Coupling Models With Special Attention to the Cooray–Rubinstein Approximation

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There are three equivalent procedures to evaluate the voltages induced by lightning on power lines, namely, the Agrawal–Price–Gurbaxani model, the Taylor–Satterwhite–Harrison model, and the Rachidi model. The Cooray–Rubinstein approximation is a procedure ...

2021

Towards artificial mechanosensing

Aleksandra Radenovic, Sanjin Marion

Carbon nanotubes with single-digit diameter embedded in a solid artificial membrane show pressure-sensitive ionic conductance that is similar to the mechanically activated currents of biological ion channels. ...

NATURE PUBLISHING GROUP2020

Prospects of Observing Ionic Coulomb Blockade in Artificial Ion Confinements

Aleksandra Radenovic, Andrey Chernev, Sanjin Marion

Nanofluidics encompasses a wide range of advanced approaches to study charge and mass transport at the nanoscale. Modern technologies allow us to develop and improve artificial nanofluidic platforms that confine ions in a way similar to single-ion channels ...

MDPI2020

Auditing Radicalization Pathways on YouTube

Robert West, Manoel Horta Ribeiro

Non-profits, as well as the media, have hypothesized the existence of a radicalization pipeline on YouTube, claiming that users systematically progress towards more extreme content on the platform. Yet, there is to date no substantial quantitative evidence ...

ASSOC COMPUTING MACHINERY2020

GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

Sean Lewis Hill, Christian Andreas Rössert, Bas-Jan Zandt, Steven Petrou

The binding of GABA (gamma-aminobutyric acid) to extrasynaptic GABA(A) receptors generates tonic inhibition that acts as a powerful modulator of cortical network activity. Despite GABA being present throughout the extracellular space of the brain, previous ...

NATL ACAD SCIENCES2020

Real-Time Multi-Ion Detection in the Sweat Concentration Range Enabled by Flexible, Printed, and Microfluidics-Integrated Organic Transistor Arrays

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Organic electrochemical transistors (OECTs) show remarkable promise as biosensors, thanks to their high signal amplification, simple architecture, and the intrinsic flexibility of the organic material. Despite these properties, their use for real-time sens ...

WILEY2020

Sampling and Reconstruction of Bandlimited Signals with Multi-Channel Time Encoding

Martin Vetterli, Adam James Scholefield, Karen Adam

Sampling is classically performed by recording the amplitude of the input at given time instants; however, sampling and reconstructing a signal using multiple devices in parallel becomes a more difficult problem to solve when the devices have an unknown sh ...

2020

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

Stewart Cole, Florence Pojer, Jérémie Piton

The EspB protein of Mycobacterium tuberculosis is a 60 kDa virulence factor, implicated in conjugation and exported by the ESX-1 system of which it may also be a component. Previous attempts to obtain high-resolution maps of EspB by cryo-electron microscop ...

2020

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