Publications related to Chemokine

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

Nikolaos Stergiopoulos, Katia Galan, Rafaela Fernandes Da Silva

Pharmacological treatments targeting CXC chemokines and the associated neutrophil activation and recruitment into atherosclerotic plaques hold promise for treating cardiovascular disorders. Therefore, we investigated whether FK866, a nicotinamide phosphori ...

Schattauer2014

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Freddy Radtke, Ute Koch, Stéphanie Claudinot

T-cell development depends upon interactions between thymocytes and thymic epithelial cells (TECs). The engagement of delta-like 4 (DL4) on TECs by Notch1 expressed by blood-borne BM-derived precursors is essential for T-cell commitment in the adult thymus ...

Wiley-Blackwell2013

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries

Christian Heinis, Petr Leiman, Shiyu Chen, Jeremy Touati, Julia Morales Sanfrutos

Bicyclic peptide ligands were found to have good binding affinity and target specificity. However, the method applied to generate bicyclic ligands based on phage-peptide alkylation is technically complex and limits its application to specialized laboratori ...

2013

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Luciano Dos Santos Aggum Capettini

Recent data support the idea that the effects of RAS are not restricted to the cardiovascular and renal systems. Importantly, RAS modulates free radical production and the cellular synthesis of several molecules such as cytokines, chemokines and transcript ...

Bentham Science Publishers2012

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

Didier Trono, Isabelle Barde, Nicola Harris, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Andrea Corsinotti, Karolina Bojkowska

Chromatin remodeling is fundamental for B-cell differentiation. In the present study, we explored the role of KAP1, the cofactor of KRAB-ZFP transcriptional repressors, in this process. B-lymphoid-specific Kap1-KO mice displayed reduced numbers of mature B ...

2012

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

Marco Pisano, Melody Swartz, Ulrike Haessler, Mingming Wu

Dendritic cell (DC) homing to the lymphatics and positioning within the lymph node is important for adaptive immunity, and is regulated by gradients of CCL19 and CCL21, ligands for CCR7. Despite the importance of DC chemotaxis, it is not well understood ho ...

2011

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

Michele De Palma, Ferdinando Pucci, Daniela Biziato

Vascular-disrupting agents (VDAs) such as combretastatin A4 phosphate (CA4P) selectively disrupt blood vessels in tumors and induce tumor necrosis. However, tumors rapidly repopulate after treatment with such compounds. Here, we show that CA4P-induced vess ...

2011

Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21

Melody Swartz, Alice Anna Tomei, Iraklis Kourtis

Tumor manipulation of host immunity is important for tumor survival and invasion. Many cancers secrete CCL21, a chemoattractant for various leukocytes and lymphoid tissue inducer cells, which drive lymphoid neogenesis. CCL21 expression by melanoma tumors i ...

2010

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Chemokine

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

COUP-TFII Controls Mouse Pancreatic beta-Cell Mass through GLP-1-beta-Catenin Signaling Pathways

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21

Graph Chatbot

Chat with Graph Search

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

COUP-TFII Controls Mouse Pancreatic beta-Cell Mass through GLP-1-beta-Catenin Signaling Pathways

Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21