Publications related to Childhood trauma

Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Background and hypothesis: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable to environmental insults during ad ...

2024

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Elenor Morgenroth

Childhood trauma (CT) has been linked to increased risk for psychosis. Moreover, CT has been linked to psychosis phenotypes such as impaired cognitive and sensory functions involved in the detection of novel sensory stimuli. Our objective was to investigat ...

SPRINGER HEIDELBERG2023

Multivariate patterns of disrupted sleep longitudinally predict affective vulnerability to psychosis in 22q11.2 Deletion Syndrome

Maude Schneider, Farnaz Delavari

22q11.2 deletion syndrome (22q11DS) contributes dramatically to increased genetic risk for psychopathology, and in particular schizophrenia. Sleep disorders, including obstructive sleep apnea (OSA), are also highly prevalent, making 22q11DS a unique model ...

ELSEVIER IRELAND LTD2023

Design of Digital Mediation Tool for Self-disclosing PTSD

Denis Gillet, Isabelle Barbara Marie-Hélène Cardia, Delphine Preissmann, Maria Gaci, Marina Fiori

Establishing trust is an important aspect of the design of technological tools for mental health, as individuals are persuaded to disclose personal distressing experiences when privacy is ensured. This work-in-progress paper presents an interdisciplinary r ...

2020

Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology

Maria del Carmen Sandi Perez, Hilal Lashuel, Johannes Burtscher, Anass Chiki, João Pedro de Matos Rodrigues, Jean-Christophe Copin

Debilitating, yet underinvestigated nonmotor symptoms related to mood/emotion, such as depression, are common in Parkinson's disease. Here, we explore the role of depression and of the amygdala, a brain region robustly linked to mood/emotion, in synucleino ...

2019

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Alessandra Griffa, Patric Hagmann, Kim Do

Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly through oxidative stress. As oxidative stress is also linked to psychosis, it may interact with CT, leading to a more severe clinic ...

National Academy of Sciences2018

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Gregor Rainer, Laura Lozano Montes, Nan Zhao

Adverse life experience increases the lifetime risk to several stress-related psychopathologies, such as anxiety or depressive–like symptom following stress in adulthood. However, the neurochemical modulations triggered by stress have not been fully charac ...

2018

Electroencephalogram (EEG) Frontal Asymmetry and Error-Related Signals Are Potential Markers of Internalizing and Externalizing Behaviors in Children: A Meta-Analysis

Michael Herzog, Ophélie Gladys Favrod

Objectives: The frontal hemispheric asymmetry and error-related components, as measured by EEG, are often considered to be biological correlates or “indicators of risk” for psychopathology. Here, we performed a meta-analysis to define specific patterns of ...

2017

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

João Miguel das Neves Duarte, Alberto Corcoba

Adverse environmental and social conditions early in life have a strong impact on health. They are major risk factors for mental diseases in adulthood and, in some cases, their effects can be transmitted across generations. The consequences of detrimental ...

Sage Publications Inc2017

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Childhood trauma

Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Multivariate patterns of disrupted sleep longitudinally predict affective vulnerability to psychosis in 22q11.2 Deletion Syndrome

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Design of Digital Mediation Tool for Self-disclosing PTSD

Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Electroencephalogram (EEG) Frontal Asymmetry and Error-Related Signals Are Potential Markers of Internalizing and Externalizing Behaviors in Children: A Meta-Analysis

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

Graph Chatbot

Chat with Graph Search

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Multivariate patterns of disrupted sleep longitudinally predict affective vulnerability to psychosis in 22q11.2 Deletion Syndrome

Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Electroencephalogram (EEG) Frontal Asymmetry and Error-Related Signals Are Potential Markers of Internalizing and Externalizing Behaviors in Children: A Meta-Analysis

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia

Design of Digital Mediation Tool for Self-disclosing PTSD