Publications related to Peptide nucleic acid

Aptamer-Functionalized Interface Nanopores Enable Amino Acid-Specific Peptide Detection

Single-molecule proteomics based on nanopore technology has made significant advances in recent years. However, to achieve nanopore sensing with single amino acid resolution, several bottlenecks must be tackled: controlling nanopore sizes with nanoscale pr ...

2024

Solid-phase peptide synthesis in 384-well plates

Christian Heinis, Edward Jeffrey Will, Anne Sofie Luise Zarda, Alexander Lund Nielsen, Sevan Mleh Habeshian, Mischa Schüttel, Gontran Sangouard

Newer solid-phase peptide synthesis and release strategies enable the production of short peptides with high purity, allowing direct screening for desired bioactivity without prior chromatographic purification. However, the maximum number of peptides that ...

Hoboken2024

Solid-State Nanopores for Biomolecular Analysis and Detection

Nako Nakatsuka, Annina Stuber

Advances in nanopore technology and data processing have rendered DNA sequencing highly accessible, unlocking a new realm of biotechnological opportunities. Commercially available nanopores for DNA sequencing are of biological origin and have certain disad ...

Springer Link2024

Recycling of Polymerase Chain Reaction (PCR) Kits

Francesco Stellacci, Weina Liu, Yong Zhu

Polymerase chain reaction (PCR) kits have been used as common diagnosing tools during the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, with daily worldwide usage in the millions. It is well known that at the beginn ...

AMER CHEMICAL SOC2023

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Bart Deplancke, Vincent Roland Julien Gardeux, Riccardo Dainese, Daniel Alpern

The present invention relates generally to the field of nucleic acid sequencing and provides oligonucleotide molecules and barcodes contained therein. These oligonucleotide molecules and barcodes molecules are useful in sequencing to identify and resolve e ...

2023

Interplay of the mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes

Maartje Martina Cornelia Bastings, Cem Tekin, Diana Kornelia Morzy, Vincenzo Caroprese

Nucleic acids and lipids function in close proximity in biological processes, as well as in nanoengineered constructs for therapeutic applications. As both molecules carry a rich charge profile, and frequently coexist in complex ionic solutions, the electr ...

ROYAL SOC CHEMISTRY2023

Core-shell Structured Chitosan-polyethylenimine Nanoparticles for Gene Delivery: Improved Stability, Cellular Uptake, and Transfection Efficiency

Sandrine Gerber, Perrine Agnes Edith Robin, Laura Camille Louise Nicolle

Gene therapy emerged as a promising treatment option for acquired and inherited diseases. The delivery of nucleic acids relies on vectors that condense and encapsulate their cargo. Especially non-viral gene delivery systems are of increasing interest. Howe ...

2022

A simple micropreparative gel electrophoresis technique for purification of proteins, nucleic acids, and bioconjugates

Ardemis Anoush Boghossian, Sayyed Hashem Sajjadi, Shang-Jung Wu, Vitalijs Zubkovs

The biochemical and biomedical fields hinge on the ability to effectively separate and purify biological macromolecules. Though this need is largely addressed with a variety of chromatographic and electrophoretic purification techniques, such techniques ar ...

2021

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules

Hatice Altug, Deepthy Kavungal, Aurélian Michel John-Herpin, Lea Katharina Von Mücke

Insights into the fascinating molecular world of biological processes are crucial for understanding diseases, developing diagnostics, and effective therapeutics. These processes are complex as they involve interactions between four major classes of biomole ...

WILEY-V C H VERLAG GMBH2021

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Peptide nucleic acid

Aptamer-Functionalized Interface Nanopores Enable Amino Acid-Specific Peptide Detection

Solid-phase peptide synthesis in 384-well plates

Solid-State Nanopores for Biomolecular Analysis and Detection

Recycling of Polymerase Chain Reaction (PCR) Kits

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Landscapes of DNA Mechanics and Genomes

Interplay of the mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes

Core-shell Structured Chitosan-polyethylenimine Nanoparticles for Gene Delivery: Improved Stability, Cellular Uptake, and Transfection Efficiency

A simple micropreparative gel electrophoresis technique for purification of proteins, nucleic acids, and bioconjugates

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules

Graph Chatbot

Chat with Graph Search

Solid-phase peptide synthesis in 384-well plates

Landscapes of DNA Mechanics and Genomes

Aptamer-Functionalized Interface Nanopores Enable Amino Acid-Specific Peptide Detection

A simple micropreparative gel electrophoresis technique for purification of proteins, nucleic acids, and bioconjugates

Solid-State Nanopores for Biomolecular Analysis and Detection

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Core-shell Structured Chitosan-polyethylenimine Nanoparticles for Gene Delivery: Improved Stability, Cellular Uptake, and Transfection Efficiency

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules

Interplay of the mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes