Publications related to Lab-on-a-chip

Single Cell Electrochemiluminescence Imaging: From the Proof-of-Concept to Disposable Device-Based Analysis

We report here the development of coreactant-based electro-generated chemiluminescence (ECL) as a surface-confined microscopy to image single cells and their membrane proteins. Labeling the entire cell membrane allows one to demonstrate that, by contrast w ...

American Chemical Society2017

Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans

Martinus Gijs, Thomas Lehnert, Matteo Cornaglia

In a typical high-throughput drug screening (HTS) process, up to millions of chemical compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit a robust dose-response, as evidenced for example by a fluorescence signal. I ...

Royal Soc Chemistry2017

The Molecular Mechanism of Nanodroplet Stability

Sylvie Roke, Yixing Chen, Halil Ibrahim Okur, David Mark Wilkins, Evangelia Zdrali

Mixtures of nano- and microscopic oil droplets in water have recently been rediscovered as miniature reaction vessels in microfluidic environments and are important constituents of many environmental systems, food, personal care, and medical products. The ...

Amer Chemical Soc2017

Multiplexed nanoplasmonic biosensor for one-step simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine

Hatice Altug, Andrea Cavallini, Alexander Belushkin, Maria Soler Aznar

Development of rapid and multiplexed diagnostic tools is a top priority to address the current epidemic problem of sexually transmitted diseases. Here we introduce a novel nanoplasmonic biosensor for simultaneous detection of the two most common bacterial ...

2017

Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis

Martinus Gijs, Raphaël Etienne Jean Trouillon, Huu Tuan Nguyen, Léa Suzanne Bernier

Chromogenic in situ hybridization (CISH) is a common technique that is used for human epidermal growth factor receptor 2 (HER2) assessment in breast cancer diagnosis. CISH is based on the enzymatic amplification of DNA markers, generating a colorimetric im ...

Elsevier2017

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Erick Antonio Garcia Cordero, Johan Frédéric Longo, Hoël Maxime Guérin, Francesco Bellando

This paper reports a novel fully integrated low power multi-sensing smart system, which, by wafer-level 3D heterogeneous integration of Ion Sensitive Fully Depleted (FD) FETs and SU-8 micro/nanofludics, achieves the first of its kind wearable multi-sensing ...

2017

Microfluidic bacterial traps for simultaneous fluorescence and atomic force microscopy

Georg Fantner, Jonathan David Adams, Oliver Peric, Mélanie Thérèse Marie Hannebelle

The atomic force microscope has become an established research tool for imaging microorganisms with unprecedented resolution. However, its use in microbiology has been limited by the difficulty of proper bacterial immobilization. Here, we have developed a ...

2017

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip

Carlotta Guiducci, George Coukos, Enrico Tenaglia, Elena Bianchi, Enrica Rollo, Alexandre Harari

Label-free approaches to assess cell properties ideally suit the requirements of cell-based therapeutics, since they permit to characterize cells with minimal perturbation and manipulation, at the benefit of sample recovery and re-employment for treatment. ...

Elsevier2017

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Lab-on-a-chip

Single Cell Electrochemiluminescence Imaging: From the Proof-of-Concept to Disposable Device-Based Analysis

Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans

Microfluidic and Electrokinetic Manipulation of Single Cells

The Molecular Mechanism of Nanodroplet Stability

Microfluidic single-cell technology in immunology and antibody screening

Multiplexed nanoplasmonic biosensor for one-step simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine

Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Microfluidic bacterial traps for simultaneous fluorescence and atomic force microscopy

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip

Graph Chatbot

Chat with Graph Search

Single Cell Electrochemiluminescence Imaging: From the Proof-of-Concept to Disposable Device-Based Analysis

Microfluidic and Electrokinetic Manipulation of Single Cells

The Molecular Mechanism of Nanodroplet Stability

Microfluidic single-cell technology in immunology and antibody screening

Multiplexed nanoplasmonic biosensor for one-step simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine

Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Microfluidic bacterial traps for simultaneous fluorescence and atomic force microscopy

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip

Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans