Concept
Computational mathematics
Related publications (132)
Computational design of novel protein–protein interactions – An overview on methodological approaches and applications
Bruno Emanuel Ferreira De Sousa Correia, Anthony Marchand, Alexandra Krina Van Hall-Beauvais
Protein–protein interactions (PPIs) govern numerous cellular functions in terms of signaling, transport, defense and many others. Designing novel PPIs poses a fundamental challenge to our understanding of molecular interactions. The capability to robustly ...
2022Computational design of vaccine immunogens
Bruno Emanuel Ferreira De Sousa Correia, Andreas Scheck, Karla Montserrat Castro Gilabert, Shuhao Xiao
Computational protein engineering has enabled the rational design of customized proteins, which has propelled both sequence-based and structure-based immunogen engineering and delivery. By discerning antigenic determinants of viral pathogens, computational ...
CURRENT BIOLOGY LTD2022On Succinct Non-interactive Arguments in Relativized Worlds
Succinct non-interactive arguments of knowledge (SNARKs) are cryptographic proofs with strong efficiency properties. Applications of SNARKs often involve proving computations that include the SNARK verifier, a technique called recursive composition. Unfort ...
SPRINGER INTERNATIONAL PUBLISHING AG2022