Concept

Traumatic brain injury

Related publications (254)

Optogenetic Dissection of the Basal Forebrain Neuromodulatory Control of Cortical Activation, Plasticity, and Cognition

The basal forebrain (BF) houses major ascending projections to the entire neocortex that have long been implicated in arousal, learning, and attention. The disruption of the BF has been linked with major neurological disorders, such as coma and Alzheimer's ...

Soc Neuroscience2015

Detecting motion intention in stroke survivors using autonomic nervous system responses

Roger Gassert, Olivier Lambercy

Individuals with severe neurologic injuries often cannot participate in robotic rehabilitation because they do not retain sufficient residual motor control to initiate the robotic assistance. In these situations, brain- and body-computer interfaces have em ...

2015

Chondroitinase gene therapy improves upper limb function following cervical contusion injury

Bernard Schneider, Nicholas David James

Chondroitin sulphate proteoglycans (CSPGs) are known to be important contributors to the intensely inhibitory environment that prevents tissue repair and regeneration following spinal cord injury. The bacterial enzyme chondroitinase ABC (ChABC) degrades th ...

Elsevier2015

A Multi-Contrast MRI Study of Microstructural Brain Damage in Patients with Mild Cognitive Impairment

Meritxell Bach Cuadra, Reto Meuli, Alessandro Daducci, Cristina Granziera, Daniel Andreas Schmitter, Alexis Roche, Guillaume Bonnier

Objectives: The aim of this study was to investigate pathological mechanisms underlying brain tissue alterations in mild cognitive impairment (MCI) using multi-contrast 3 T magnetic resonance imaging (MRI). Methods: Forty-two MCI patients and 77 healthy co ...

Elsevier2015

Diminazene Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Injury

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

IntroductionAngiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin angiotensin system, which breaks down angiotensin II and forms angiotensin-(1-7). In erectile tissues, it has been documented that angiotensin II contributes to the development ...

Wiley-Blackwell2015

A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies

Francesco Piraino

The intricate process of wound healing involves activation of biological pathways that work in concert to regenerate a tissue microenvironment consisting of cells and external cellular matrix (ECM) with enzymes, cytokines, and growth factors. Distinct stag ...

Hindawi Publishing Corp2015

Moving Brain-Controlled Devices Outside the Lab: Principles and Applications

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Robert Leeb, Inaki Asier Iturrate Gil, Serafeim Perdikis

This chapter provides an overview of the functionality and the underlying principles of the brain-computer interfaces (BCI) developed by the Chair in Non-Invasive Brain-Machine Interface (CNBI) of the Swiss Federal Institute of Technology (EPFL), as well a ...

Springer Netherlands2015

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

Rolf Gruetter, Cristina Ramona Cudalbu, Mélanie Craveiro

In vivo (1)H MR spectroscopy allows the non invasive characterization of brain metabolites and it has been used for studying brain metabolic changes in a wide range of neurodegenerative diseases. The prion diseases form a group of fatal neurodegenerative d ...

Springer Verlag2015

Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain

Pierre Magistretti, Jocelyne Bloch, Reto Meuli

Experimental evidence suggests that lactate is neuroprotective after acute brain injury; however, data in humans are lacking. We examined whether exogenous lactate supplementation improves cerebral energy metabolism in humans with traumatic brain injury (T ...

Springer Verlag2014

Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain

Yohan Van de Looij

Objective Lactoferrin (Lf) is an iron-binding glycoprotein secreted in maternal milk presenting anti-inflammatory and antioxidant properties. It shows efficient absorption into the brain from nutritional source. Brain injury frequently resulting from cereb ...

2014

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