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Related publications (7)

Inferring Transmission Fitness Advantage of SARS-CoV-2 Variants of Concern in Wastewater Using Digital PCR

Tamar Kohn, Xavier Fernandez Cassi, Timothy R. Julian

Throughout the global COVID-19 pandemic, SARS-CoV-2 genetic variants of concern (VOCs) have repeatedly and independently arisen. VOCs are characterized by increased transmissibility, increased virulence, or reduced neutralization by antibodies obtained fro ...

2022

Detection and surveillance of SARS-CoV-2 genomic variants in wastewater

Tamar Kohn, Xavier Fernandez Cassi, Federica Cariti, Alex Tunas Corzon, Timothy R. Julian, Carola Bänziger

The emergence of SARS-CoV-2 mutants with altered transmissibility, virulence, or immunogenicity emphasizes the need for early detection and epidemiological surveillance of genomic variants. Wastewater samples provide an opportunity to assess circulating vi ...

2021

Topology Optimization for Coils of Electric Machine with Level-set Method

Yves Perriard, Adrien Jean-Michel Thabuis, Xiaotao Ren

This work studies the level-set based topology optimization for the optimal layout of winding in electric motor. The functional to optimize is to maximize the torque in the air-gap. The coil domain is initiated by a level set function. The time evolutionar ...

IEEE2019

On the (un) predictability of a large intragenic fitness landscape

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski

The study of fitness landscapes, which aims at mapping genotypes to fitness, is receiving ever-increasing attention. Novel experimental approaches combined with next-generation sequencing (NGS) methods enable accurate and extensive studies of the fitness e ...

Natl Acad Sciences2016

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong

Disinfection is an important strategy to control the environmental transmission of human viruses. Specifically, UV254 is increasingly used to disinfect from clinical items or surfaces to drinking water. RNA virus populations have high mutation rates and la ...

2016

Theoretical and Experimental Studies of Dendritic Metacommunities

Francesco Carrara

The present thesis deals with the understanding of the origins and the mechanisms of maintenance of biodiversity in natural landscapes, in particular by identifying key processes that define large-scale patterns of abundance and diversity. Biological commu ...

EPFL2013

Exponential Natural Evolution Strategies

Daniël Pieter Wierstra, Tom Schaul

The family of natural evolution strategies (NES) offers a principled approach to real-valued evolutionary optimization by following the natural gradient of the expected fitness. Like the well-known CMA-ES, the most competitive algorithm in the field, NES c ...

2010

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