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Hydrogels are cross-linked, water-swollen polymer networks. Hydrogels with high mechanical and viscous dissipation properties are of great interest for mechanically control drug release systems. Since hydrogels are 3D polymer network with high amount of wa ...
This paper reports on the cell uptake and trafficking properties of a series of non-covalent polymer-drug conjugates. These nanomedicines are composed of a poly(N-(2-hydroxypropyl)methacrylamide) backbone functionalized with multiple copies of a drug. The ...
Biocomposite hydrogels with carboxymethylated, nanofibrillated cellulose (c-NFC) powder were prepared by UV polymerization of N-vinyl-2-pyrrolidone with Tween 20 trimethacrylate as a cross-linking agent for replacement of the native, human nucleus pulposus ...
The flow and failure behaviour of replicated pure aluminium foams in the presence of holes and notches is explored, varying the pore size and the notch depth or hole radius. Flat dog-bone tensile specimens containing a cylindrical hole, and cylindrical V-n ...
The dispersion of highly hydrophobic carbon materials such as carbon nanotubes in biological media is a challenging issue. Indeed, the nonspecific adsorption of proteins occurs readily when the nanotubes are introduced in biological media; therefore, a met ...
Silicone rubber films with graded and localized mechanical properties are prepared using two-part polydimethylsiloxane (PDMS) elastomer, photoinhibitor compounds and conventional photolithography. First the un-cross-linked PDMS is mixed with benzophenone. ...
Polymer therapeutics, including polymeric drugs and polymer-protein conjugates, are clinically established as first-generation nanomedicines. Knowing that the coiled-coil peptide motif is fundamentally important in the regulation of many cellular and patho ...
Fibrin has been long used clinically for hemostasis and sealing, yet extension of use in other applications has been limited due to its relatively rapid resorption in vivo, even with addition of aprotinin or other protease inhibitors. We report an engineer ...
Poly(ethylene-co-vinyl acetate) (EVA) is the primary polymer used for encapsulation of photovoltaic (PV) modules. Its degree of cross-linking (gel content) is taken as a major quality reference. The EVA gel content is normally measured by Soxhlet extractio ...
The intervertebral disc (IVD), which provides flexibility to the spine and facilitates damping and motion, is composed of two distinct structures: the annulus fibrosus (AF) and the nucleus pulposus (NP). The AF, which is fibrous and elastic, confines the N ...