MicrosatelliteA microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from one to six or more base pairs) are repeated, typically 5–50 times. Microsatellites occur at thousands of locations within an organism's genome. They have a higher mutation rate than other areas of DNA leading to high genetic diversity. Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists and in genetic genealogy, or as simple sequence repeats (SSRs) by plant geneticists.
23andMe23andMe Holding Co. is a publicly held personal genomics and biotechnology company based in South San Francisco, California. It is best known for providing a direct-to-consumer genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism genotyping, to generate reports relating to the customer's ancestry and genetic predispositions to health-related topics. The company's name is derived from the 23 pairs of chromosomes in a diploid human cell.
SomalisThe Somalis (Soomaalida 𐒈𐒝𐒑𐒛𐒐𐒘𐒆𐒖, صوماليون) are an ethnic group native to the Horn of Africa who share a common ancestry, culture and history. The East Cushitic Somali language is the shared mother tongue of ethnic Somalis, which is part of the Cushitic branch of the Afroasiatic language family, and are predominantly Sunni Muslim. They form one of the largest ethnic groups on the African continent, and cover one of the most expansive landmasses by a single ethnic group in Africa.
Mitochondrial EveIn human genetics, the Mitochondrial Eve (also mt-Eve, mt-MRCA) is the matrilineal most recent common ancestor (MRCA) of all living humans. In other words, she is defined as the most recent woman from whom all living humans descend in an unbroken line purely through their mothers and through the mothers of those mothers, back until all lines converge on one woman. In terms of mitochondrial haplogroups, the mt-MRCA is situated at the divergence of macro-haplogroup L into L0 and L1–6.
Y chromosomeThe Y chromosome is one of two sex chromosomes in therian mammals and other organisms. The other sex chromosome is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers male development. The DNA in the human Y chromosome is composed of about 62 million base pairs, making it similar in size to chromosome 19.
Genographic ProjectThe Genographic Project, launched on 13 April 2005 by the National Geographic Society and IBM, was a genetic anthropological study (sales discontinued on 31 May 2019) that aimed to map historical human migrations patterns by collecting and analyzing DNA samples. The final phase of the project was Geno 2.0 Next Generation. Upon retirement of the site, 1,006,542 participants in over 140 countries had joined the project.
PatrilinealityPatrilineality, also known as the male line, the spear side or agnatic kinship, is a common kinship system in which an individual's family membership derives from and is recorded through their father's lineage. It generally involves the inheritance of property, rights, names, or titles by persons related through male kin. This is sometimes distinguished from cognate kinship, through the mother's lineage, also called the spindle side or the distaff side. A patriline ("father line") is a person's father, and additional ancestors, as traced only through males.
Ancestry.comAncestry.com LLC is an American genealogy company based in Lehi, Utah. The largest for-profit genealogy company in the world, it operates a network of genealogical, historical records, and related genetic genealogy websites. In November 2018, the company said to have provided access to approximately 10 billion historical records, to have 3 million paying subscribers, and to have sold 18 million DNA kits to customers. By 2022, this number had risen to 30 billion records according to the company.
Human mitochondrial DNA haplogroupIn human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z.
Genetic history of EuropeThe genetic history of Europe includes information around the formation, ethnogenesis, and other DNA-specific information about populations indigenous, or living in Europe. The most significant recent dispersal of modern humans from Africa gave rise to an undifferentiated "non-African" lineage by some 70–50 ka (70-50,000 years ago). By about 50–40 ka a West Eurasian lineage had emerged, as had a separate East Eurasian lineage. Both East and West Eurasians acquired Neanderthal admixture in Europe and Asia.