Concept

Free-running sleep

Related publications (15)

Global brain dynamics under visual entrainment

Cognitive and perceptual functions depend on the momentary dynamics of the brain. A typical approach to investigate these dynamics is through the so-called method of entrainment. In entrainment, a rhythmic stimulation (e.g., a periodic visual or auditory s ...

2022

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Jonathan Paz Montoya, Howard Riezman

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in ...

PUBLIC LIBRARY SCIENCE2022

Integrating non-visual effects of light in the automated daylight-responsive control of blinds and electric lighting

Marta Benedetti

The use of daylight in buildings is important because it contributes to energy savings by reducing the use of electric lighting and space heating. It also impacts on biological functions and on well-being. Indeed, light not only allows vision, but has non- ...

EPFL2021

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

Daniel Sage

Circadian clocks operative in pancreatic islets participate in the regulation of insulin secretion in humans and, if compromised, in the development of type 2 diabetes (T2D) in rodents. Here we demonstrate that human islet alpha- and beta-cells that bear a ...

NATL ACAD SCIENCES2020

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

CELL PRESS2019

Evidence for Rhythmicity Pacemaker in the Calcification Process of Scleractinian Coral

Anders Meibom, Jaroslaw Hubert Stolarski, Isabelle Domart-Coulon

Reef-building scleractinian (stony) corals are among the most efficient bio-mineralizing organisms in nature. The calcification rate of scleractinian corals oscillates under ambient light conditions, with a cyclic, diurnal pattern. A fundamental question i ...

Nature Publishing Group2016

Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls

Lorette Leon

This study examined the effect of optic nerve disease, hence retinal ganglion cell loss, on nonvisual functions related to melanopsin signalling. Test subjects were patients with bilateral visual loss and optic atrophy from either hereditary optic neuropat ...

Nature Publishing Group2015

Dynamics of the head of gravity currents

Mário Jorge Rodrigues Pereira Da Franca, Helena Isabel Dos Santos Nogueira, Claudia Adduce

The present work experimentally investigates the dynamics of unsteady gravity currents produced by lock-release of a saline mixture into a fresh water tank. Seven different experimental runs were performed by varying the density of the salinemixture in the ...

Springer Verlag2013

Effect of Network Architecture on Synchronization and Entrainment Properties of the Circadian Oscillations in the Suprachiasmatic Nucleus

Marc Hafner

In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus constitutes the central circadian pacemaker. The SCN receives light signals from the retina and controls peripheral circadian clocks (located in the cortex, the pineal gland, the liver, the ...

Public Library of Science2012

Effects of prior light exposure on early evening performance, subjective sleepiness, and hormonal secretion

Jean-Louis Scartezzini, Mirjam Münch, Friedrich Linhart, Apiparn Borisuit

In sighted humans, light intensity, timing, exposure duration, and spectral composition of light are important to entrain the endogenous circadian pacemaker to the 24-h day-night cycle. We tested the impact of two realistic office lighting conditions durin ...

American Psychological Association2012

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