Related publications (40)

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Camille Véronique Bernadette Goemans, Florian Huber

By acquiring or evolving resistance to one antibiotic, bacteria can become resistant to a second one, due to shared underlying mechanisms. This is called cross-resistance (XR) and further limits therapeutic choices. The opposite scenario, in which initial ...
2024

Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

Maria del Carmen Sandi Perez, Bernard Schneider, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Elias Georges Gebara, Marie-Isabelle Guillot de Suduiraut, Alessandro Chioino, Sriparna Ghosal, Eva Ramos Fernandez

The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc links anxiety with social competitiveness, and the mitochondrial fusion protein mitofusin 2 (Mfn2) in NAc neurons ...
2023

Development of stimuli-responsive chemistry for tumor-targeted immunotherapy

Céline Jasmin Prange

Cancer immunotherapy is the science of boosting the immune response of patients to fight cancer. Recent advances have brought up treatments with huge success in the clinic. Patients with ad-vanced-stage cancers were long-term cured through checkpoint inhib ...
EPFL2023

Dopamine and Methamphetamine Differentially Affect Electron Transport Chain Complexes and Parkin in Rat Striatum: New Insight into Methamphetamine Neurotoxicity

Bernard Schneider, Akhil Sharma

Methamphetamine (METH) is a highly abused psychostimulant that is neurotoxic to dopaminergic (DAergic) nerve terminals in the striatum and increases the risk of developing Parkinson's disease (PD). In vivo, METH-mediated DA release, followed by DA-mediated ...
MDPI2022

Probing the Limits of Optical Loss in Ion-Sliced Thin-film Lithium Niobate

Tobias Kippenberg, Guanhao Huang, Mikhail Churaev, Junqiu Liu, Zelin Tan, Di Zhu

We measured the absorption-limited loss at telecommunication wavelengths for thin-film lithium niobate micro-ring resonators using Kerr-calibrated linear response technique. We find the average absorption loss-rate kappa(abs)/2 pi to be 3.65 +/- 0.70 MHz, ...
IEEE2021

Sensorimotor Induction of Auditory Misattribution in Early Psychosis

Olaf Blanke, Andrea Serino, Alessandra Griffa, Fosco Bernasconi, Patric Hagmann, Kim Do, Roy Salomon, Giulio Rognini, Silvia Marchesotti, Pierre Progin

Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hall ...
2020

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