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Mixed inhibition

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Mixed inhibition

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Antibody-peptide conjugates for targeted inhibition of cysteine proteases

Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Allosteric regulation and targeting of Bruton's tyrosine kinase (Btk) in B-cell lymphoma

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

The evolution of multiple active site configurations in a designed enzyme

Kinetics, Mechanics and Micro-structure of Bio-cemented Soils

Computational Investigation of Intracellular Signalling Cascades

A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance