Larkana (لاڙڪاڻو; ) is a city located in the Sind province of Pakistan. It is the 15th largest city of Pakistan by population. It is home to the Indus Valley civilization site Mohenjo-daro. The historic Indus River flows in east and south of the city. The city is located within Larkana District. Formerly known as "Chandka", Larkana is located on the south bank of the Ghar canal, about south of the town Shikarpur, and northeast of Mehar. According to the 2017 Census of Pakistan, its population is 490,508. Therefore, it is the fourth most populated city of Sindh province after Karachi, Hyderabad, and Sukkur. Moreover, Larkana city has been placed as fifteenth largest of Pakistan during Census 2017. Larkana is situated at Latitude 24 56' 00' and Longitude 67 11' 00'. It is situated in northwest part of Sindh and it has own division. It is also included in Upper Sindh. Larkana has a hot desert climate (Köppen climate classification BWh) with sweltering summers and mild winters. The highest recorded temperature is , recorded in May 1998 and the lowest recorded temperature is , recorded in January 1929. The average annual rainfall is , and mainly occurs in the monsoon season (July to September). The highest annual rainfall ever is , recorded in 2022 (some areas of the city got more than 1000 mm of annual rainfall in 2022) and the lowest annual rainfall ever is , recorded in 1938. Rice is the most famous crop of Larkana. Peas, rape, Mustered, and Sunflowers are also grown there. The deputy commissioner is the head of the District Administrative system. Ms Rabia Sial is the present deputy commissioner of Larkana. The district of Larkana is administratively subdivided into the following talukas: Dokri Bakrani Larkana Ratodero Several old and new schools, colleges, as well as university are functioning in the city for both boys and girls. Many are private and public institutions.