Concept
Maximum parsimony (phylogenetics)
Related publications (62)
Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania
The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. We aim ...
Nature Portfolio2024Spatiotemporal wildfire modeling through point processes with moderate and extreme marks
Accurate spatiotemporal modeling of conditions leading to moderate and large wildfires provides better understanding of mechanisms driving fire-prone ecosystems and improves risk management. Here, we develop a joint model for the occurrence intensity and t ...
2023Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load
Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising selection, with a typical opti ...
OXFORD UNIV PRESS2022Extracting phylogenetic dimensions of coevolution reveals hidden functional signals
Anne-Florence Raphaëlle Bitbol
Despite the structural and functional information contained in the statistical coupling between pairs of residues in a protein, coevolution associated with function is often obscured by artifactual signals such as genetic drift, which shapes a protein's ph ...
NATURE PORTFOLIO2022