Greenville is a home rule-class city in Muhlenberg County, Kentucky, in the United States. It is the seat of its county. The population was 4,492 as of the 2020 census.
The town was settled in 1799 on an estate donated by local landowner William Campbell in order to establish a seat of government for a new county. Greenville was not established by the state assembly until 1812, however. It was incorporated as a city in 1848.
The city was probably named for the Revolutionary War general Nathanael Greene. Local lore holds it was named by Campbell's wife after the abundant forests seen from the town's hilltop location.
Greenville is located in central Muhlenberg County at (37.207158, -87.176499). It is bordered to the northeast by the city of Powderly.
U.S. Route 62 passes through Greenville as Main Street and Hopkinsville Street. It leads northeast through Powderly to Central and west to Nortonville. Kentu