Publications related to Natural product

Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Anders Meibom, Stéphane Laurent Escrig, Charlotte Madeleine Nicole Lekieffre, Michael Kühl

Some sacoglossan sea slugs incorporate intracellular functional algal chloroplasts, a process termed kleptoplasty. "Stolen" chloroplasts (kleptoplasts) can remain photosynthetically active up to several months, contributing to animal nutrition. Whether thi ...

NATURE PUBLISHING GROUP2020

Reactions of pyrrole, imidazole, and pyrazole with ozone: kinetics and mechanisms

Urs von Gunten, Peter Rudolf Tentscher, Sung Eun Lim

Five-membered nitrogen-containing heterocyclic compounds (azoles) belong to potential moieties in complex structures where transformations during ozonation can occur. This study focused on the azole-ozone chemistry of pyrrole, imidazole, and pyrazole as mo ...

ROYAL SOC CHEMISTRY2020

Asymmetric Alkenyl C−H Functionalization by Cp x Rh III forms 2 H ‐Pyrrol‐2‐ones through [4+1]‐Annulation of Acryl Amides and Allenes

Nicolai Cramer, Yang Liu, Shouguo Wang

An efficient CpxRhIII‐catalyzed enantioselective alkenyl C−H functionalization/[4+1] annulation of acryl amides and allenes is reported. The described transformation provides straightforward access to enantioenriched α,β‐unsaturated‐γ‐lactams bearing a qua ...

2019

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

Qian Wang, Jieping Zhu, Cyril Piemontesi, Guang Li

Controlling the cis C20/C21 relative stereochemistry remains an unsolved issue in the synthesis of eburnane-type indole alkaloids. Provided herein is a simple solution to this problem by developing a unified and diastereoselective synthesis of four represe ...

2019

Chapter 16: Microbial Production of Flavonoids: Engineering Strategies for Improved Production

Edgard Gnansounou, Binod Parameswaran

Flavonoids are natural plant-derived compounds which have immense applications in pharmaceutical industry and have attracted the attention of both the industry and researchers involved in all fields of biology and medicine. Microbial production systems can ...

Wiley2019

Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

Gerardo Turcatti, Benjamin Rappaz, Fabien Kuttler, Damiano Banfi, Pierre Marquet, Pascal Jourdain

The ionotropic GABA(A) receptors represent the main target for different groups of widely used drugs having hypnotic and anxiolytic effects. So far, most approaches used to assess GABA activity involve invasive low -throughput electrophysiological techniqu ...

2019

Extrapolating the Fragment-Based Approach to Inorganic Drug Discovery

Paul Joseph Dyson, Lucinda Kate Batchelor

The fragment-based approach is a well-established strategy for organic drug discovery. Recent studies have shown that this approach also has considerable potential in medicinal inorganic chemistry, and yet the approach has not been formally described. Here ...

ELSEVIER2019

Nickel-Catalyzed Regioselective Hydroalkylation and Hydroarylation of Alkenyl Boronic Esters

Xile Hu, Srikrishna Bera

Metal hydride catalyzed hydrocarbonation reactions of alkenes are an efficient approach to construct new carbon-carbon bonds from readily available alkenes. However, the regioselectivity of hydrocarbonation remains challenging to be controlled. In nickel h ...

WILEY-V C H VERLAG GMBH2019

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Natural product

Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Reactions of pyrrole, imidazole, and pyrazole with ozone: kinetics and mechanisms

Asymmetric Alkenyl C−H Functionalization by Cp x Rh III forms 2 H ‐Pyrrol‐2‐ones through [4+1]‐Annulation of Acryl Amides and Allenes

Recent Advances in Catalytic Enantioselective Rearrangement

Development of New Strategies of Umpolung with Cyclic Hypervalent Iodine Reagents

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

Chapter 16: Microbial Production of Flavonoids: Engineering Strategies for Improved Production

Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

Extrapolating the Fragment-Based Approach to Inorganic Drug Discovery

Nickel-Catalyzed Regioselective Hydroalkylation and Hydroarylation of Alkenyl Boronic Esters

Graph Chatbot

Chat with Graph Search

Chapter 16: Microbial Production of Flavonoids: Engineering Strategies for Improved Production

Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Reactions of pyrrole, imidazole, and pyrazole with ozone: kinetics and mechanisms

Asymmetric Alkenyl C−H Functionalization by Cp x Rh III forms 2 H ‐Pyrrol‐2‐ones through [4+1]‐Annulation of Acryl Amides and Allenes

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

Recent Advances in Catalytic Enantioselective Rearrangement

Development of New Strategies of Umpolung with Cyclic Hypervalent Iodine Reagents

Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

Nickel-Catalyzed Regioselective Hydroalkylation and Hydroarylation of Alkenyl Boronic Esters

Extrapolating the Fragment-Based Approach to Inorganic Drug Discovery