Lathrop is a city in Clinton County, Missouri, and is part of the Kansas City metropolitan area within the United States. The population was 2,086 at the 2010 census.
Lathrop was platted in 1867 as a stop on the Cameron Cutoff Branch of the Hannibal and St. Joseph Railroad. It was named for John L. Lathrop, treasurer for the railroad. A post office called Lathrop has been in operation since 1868.
In the early 1900s it was considered the "Mule Capital of the World" after the firm of Guyton and Harrington sold 180,000 mules and 170,000 horses to the British Army during World War I. The cousins J.D. Guyton and W.R. Harrington owned 4,700 acres near Lathrop. They also supplied mules to the British during the Boer War. Among the facilities in Lathrop were three barns stabling 1,000 mules each and a 496 foot long hay barn. The British had a formal contract for a remount station in Lathrop. The business had facilities at 17th and Wyandotte in Kansas City and had a shi