Florida is a village in Monroe County, Missouri, United States. It is located at the intersection of Missouri Route 107 and State Route U on the shores of Mark Twain Lake. The population was 200, per the census data in the 1911 Cram's World Atlas. The population was however down to nine residents according to the 2000 United States Census, and following the 2010 Census, the village was reported as uninhabited. The Mark Twain Birthplace State Historic Site is located in Florida, with Mark Twain State Park nearby.
Mark Twain was born in Florida in 1835. He said his birthplace was "a nearly invisible village" and "The village contained a hundred people and I increased the population by 1 per cent. It is more than many of the best men in history could have done for a town".
The village of Florida was laid out in the winter of 1831. The community took its name from the state of Florida. The founders were Robert Donaldson, Joseph Grigsby, Hugh A. Hickman, a Doctor Keen