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Adenylyl cyclase type 5 knockout mice (AC5 KO) live longer and are stress resistant, similar to calorie restriction (CR). AC5 KO mice eat more, but actually weigh less and accumulate less fat compared to WT mice. CR applied to AC5 KO result in rapid decrea ...
This project deals with the finite element approximation of an inverse problem for the monodomain equation, which models the propagation of the electrical potential in the cardiac muscle. The goal consists in recovering the shape of an infarcted area inside ...
Stability of the shoulder, more precisely the glenohumeral joint, can only be achieved in case of healthy and well coordinated muscular activity in the upper limb. Degenerative deseases like osteoarthritis, muscle deficiencies or injuries can lead to insta ...
Skeletal muscle exhibits a high plasticity and accordingly can quickly adapt to different physiological and pathological stimuli by changing its phenotype largely through diverse epigenetic mechanisms. The nuclear receptor corepressor 1 (NCoR1) has the abi ...
The study verifies the development of active axial stress in the wall of mouse aorta over a range of physiological loads when the smooth muscle cells are stimulated to contract. The results obtained show that the active axial stress is virtually independen ...
By improving spatial and anatomical specificity, localized spectroscopy can enhance the power and accuracy of the quantitative analysis of cellular metabolism and bioenergetics. Localized and nonlocalized dynamic 31P magnetic resonance spectroscopy using a ...
Specialized contractile function and increased mitochondrial number and oxidative capacity are hallmark features of myocyte differentiation. The estrogen-related receptors (ERRs) can regulate mitochondrial biogenesis or mitochondrial enzyme expression in s ...
Using a small, but very instructive experiment, it is demonstrated that laser-Doppler flowmetry (LDF) at large interoptode spacing represents a unique tool for new investigations of thermoregulatory processes modulating the blood flow of small muscle masse ...
A biomechanical model of the human shoulder complex is proposed for quasi-static and dynamic estimation of the muscle forces and joint reaction forces in the glenohumeral joint. The model bases itself on the Garner & Pandy model but adds a dynamic layer. T ...
The shoulder is often described as the most complex human joint because of its anatomy and the high number of muscles participating in arm movements. The anatomy and the development of muscles depend on personal characteristics and the style of living. The ...
