Publications related to Hormone

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Michaël Unser, Daniel Sage, Cédric Gobet, Frédéric Bruno Martin Gachon

A critical role of circadian oscillators in orchestrating insulin secretion and islet gene transcription has been demonstrated recently. However, these studies focused on whole islets and did not explore the interplay between α-cell and β-cell clocks. We p ...

2017

Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation

Bruno Lemaitre, Wen Bin Chng, Xiaoxue Li

Animals rely on complex signaling network to mobilize its energy stores during starvation. We have previously shown that the sugar-responsive TGF beta/Activin pathway, activated through the TGF beta ligand Dawdle, plays a central role in shaping the post-p ...

2017

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Cathrin Brisken, Georgios Sflomos, Ayyakkannu Ayyanan, Laura Battista, Maryse Fiche, Valentina Scabia, Valérian Charles Robert Dormoy

Seventy-five percent of breast cancers are estrogen receptor α positive (ER(+)). Research on these tumors is hampered by lack of adequate in vivo models; cell line xenografts require non-physiological hormone supplements, and patient-derived xenografts (PD ...

Elsevier2016

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids

Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Meltem Weger

Altered daily patterns of hormone action are suspected to contribute to metabolic disease. It is poorly understood how the adrenal glucocorticoid hormones contribute to the coordination of daily global patterns of transcription and metabolism. Here, we exa ...

Public Library Science2016

Oral transfer of chemical cues, growth proteins and hormones in social insects

Laure Menin, Oksana Riba Grognuz, Laurent Keller

Social insects frequently engage in oral fluid exchange trophallaxis between adults, and between adults and larvae. Although trophallaxis is widely considered a food-sharing mechanism, we hypothesized that endogenous components of this fluid might underlie ...

Elife Sciences Publications Ltd2016

A Gating Mechanism of the Serotonin 5-HT3 Receptor

Horst Vogel, Shuguang Yuan

Our recently solved high-resolution structure of the serotonin 5-HT3 receptor (5-HT3R) delivered the first detailed structural insights for a mammalian pentameric ligand-gated ion channel. Based on this structure, we here performed a total of 2.8-μs all-at ...

Cell Press2016

On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites

Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong

Like other animals, C. elegans nematodes have the ability to socially interact and to communicate through exchange and sensing of small soluble signaling compounds that help them cope with complex environmental conditions. For the time being, worm biocommu ...

Royal Soc Chemistry2016

Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination

Florence Pojer

Brassinosteroids are plant steroid hormones that control many aspects of plant growth and development, and are perceived at the cell surface by the plasma membrane-localized receptor kinase BRI1. Here we show that BRI1 is post-translationally modified by K ...

Nature Publishing Group2015

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Hormone

A Click Cage: Organelle‐Specific Uncaging of Lipid Messengers

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation

Systems Phytohormone Responses to Mitochondrial Proteotoxic Stress

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids

Oral transfer of chemical cues, growth proteins and hormones in social insects

A Gating Mechanism of the Serotonin 5-HT3 Receptor

On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites

Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination

Graph Chatbot

Chat with Graph Search

A Click Cage: Organelle‐Specific Uncaging of Lipid Messengers

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Systems Phytohormone Responses to Mitochondrial Proteotoxic Stress

Oral transfer of chemical cues, growth proteins and hormones in social insects

A Gating Mechanism of the Serotonin 5-HT3 Receptor

On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites

Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination

Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids