Duboistown is a borough in Lycoming County, Pennsylvania, United States. The population was 1,198 at the 2020 census. It is part of the Williamsport, Pennsylvania Metropolitan Statistical Area.
Duboistown (pronounced 'doo-BOYS town') is named for its founders John and Mathias DuBois who bought of land between 1852 and 1857. The DuBois brothers divided their land into parcels and established the village that bears their name. John DuBois left the West Branch Susquehanna Valley before Duboistown was established as a borough. He sold his business interests and moved west to Clearfield County. He became quite wealthy and the city of DuBois was named in his honor.
The town built by the DuBois brothers and established as a borough in 1878 is by no means the beginning of the history of Duboistown. It is situated at the mouth of Mosquito Run on the banks of the West Branch Susquehanna River. A tribe of Susquehannock Indians had what appears to have been a fairly major settl