Publications related to Inhalational anesthetic

Prediction of Dispersion Rate of Airborne Nanoparticles in a Gas-Liquid Dual-Microchannel Separated by a Porous Membrane: A Numerical Study

Carlotta Guiducci, Zohreh Sheidaei

Recently, there has been increasing attention toward inhaled nanoparticles (NPs) to develop inhalation therapies for diseases associated with the pulmonary system and investigate the toxic effects of hazardous environmental particles on human lung health. ...

MDPI2022

Measuring Glycolytic Activity with Hyperpolarized [2H7, U-13C6] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions

Rolf Gruetter, Bernard Lanz, Andrea Capozzi, Yves Pilloud, Emmanuelle Ines Flatt

Glucose is the primary fuel for the brain; its metabolism is linked with cerebral function. Different magnetic resonance spectroscopy (MRS) techniques are available to assess glucose metabolism, providing complementary information. Our first aim was to in ...

2021

Pencil Graphite Needle-Shaped Biosensor for Anaesthetic Monitoring in Human Serum

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Direct and online continuous monitoring of anaesthetic intake by the patient's blood stream improves practices in the critical procedure of anaesthesia. Several systems have been proposed to address this challenge. Electrochemical techniques are highly app ...

IEEE2020

Live Demonstration: Quasi-Digital Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Danilo Demarchi, Simone Aiassa, Francesco Grassi

The live demonstration presents the innovative concept of a portable pen-device able to sense anaesthetic compounds over time for improved anaesthesiology practice. A custom Printed Circuit Board (PCB) manage in the event-based quasi-digital domain the sam ...

IEEE2019

Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Francesca Stradolini, Danilo Demarchi, Abuduwaili Tuoheti, Simone Aiassa

Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to ...

IEEE2019

Astrocytic and neuronal oxidative metabolism are coupled to the rate of glutamate-glutamine cycle in the tree shrew visual cortex

Rolf Gruetter, Gregor Rainer, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay, Anne Catherine Clerc

Astrocytes play an important role in glutamatergic neurotransmission, namely by clearing synaptic glutamate and converting it into glutamine that is transferred back to neurons. The rate of this glutamate–glutamine cycle (VNT) has been proposed to couple t ...

Wiley-Blackwell2018

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Grégoire Courtine, Eduardo Martin Moraud, Tomislav Milekovic, Shiqi Sun

Parkinson's disease motor symptoms are treated with levodopa, but long‐term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophys ...

2018

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employ ...

Wiley-Blackwell2017

Fixation of nitrous oxide by mesoionic and carbanionic N-heterocyclic carbenes

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Euro Solari, Giacomo Cecot, Léonard Yannick Maurice Eymann

A ditopic carbanionic N-heterocyclic carbene was found to react with the inert gas nitrous oxide, resulting in a stable covalent adduct with two intact N2O groups attached to the heterocycle. Mesoionic N-heterocyclic carbenes derived from C2-arylated 1,3-b ...

Royal Soc Chemistry2017

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