Lake Andes is a city in, and the county seat of, Charles Mix County, South Dakota, United States. The population was 710 at the 2020 census.
The town took its name from Lake Andes which some say derives its name from a pioneer hunter named Handy, while others believe was named after Edward Andes, a fur company official. The town and the lake are referred to as Bde Ihaƞke in Dakota language of the native Yankton Sioux Tribe.
YST Transit serves the community and connects riders to Marty, Ravinia and Wagner as well.
Lake Andes is located within the Yankton Sioux Tribe's reservation.
According to the United States Census Bureau, the city has a total area of , of which is land and is water.
As of the census of 2010, there were 879 people, 316 households, and 195 families residing in the city. The population density was . There were 361 housing units at an average density of . The racial makeup of the city was 40.8% White, 0.1% African American, 52.7% Native American, 0.1% Asian, 0.1% from other races, and 6.1% from two or more races. Hispanic or Latino of any race were 2.8% of the population.
There were 316 households, of which 40.2% had children under the age of 18 living with them, 28.2% were married couples living together, 26.6% had a female householder with no husband present, 7.0% had a male householder with no wife present, and 38.3% were non-families. 34.8% of all households were made up of individuals, and 19.6% had someone living alone who was 65 years of age or older. The average household size was 2.52 and the average family size was 3.24.
The median age in the city was 33.8 years. 32.1% of residents were under the age of 18; 7.7% were between the ages of 18 and 24; 21.6% were from 25 to 44; 19.9% were from 45 to 64; and 18.7% were 65 years of age or older. The gender makeup of the city was 47.9% male and 52.1% female.
As of the census of 2000, there were 819 people, 320 households, and 181 families residing in the city. The population density was . There were 369 housing units at an average density of .