Chronotype

Natural sciences
Biology
Chronobiology
Topics in chronobiology

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Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health

Frédéric Bruno Martin Gachon

Chrono-nutrition is an emerging research field in nutritional epidemiology that encompasses 3 dimensions of eating behavior: timing, frequency, and regularity. To date, few studies have investigated how an individual's circadian typology, i.e., one's chron ...

OXFORD UNIV PRESS2019

The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism

Felix Naef, Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Jake Yeung

The circadian clock and associated feeding rhythms have a profound impact on metabolism and the gut microbiome. To what extent microbiota reciprocally affect daily rhythms of physiology in the host remains elusive. Here, we analyzed transcriptome and metab ...

Cell Press2019

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

2019

Differential Heating Drives Downslope Flows that Accelerate Mixed-LayerWarming in Ice-Covered Waters

Alfred Johny Wüest, Damien Bouffard, Hugo Nicolás Ulloa Sánchez, Kraig Bates Winters

In ice-covered lakes, penetrative radiation warms fluid beneath a diffusive boundary layer, thereby increasing its density and providing energy for convection in a diurnally active, deepening mixed layer. Shallow regions are differentially heated to warmer ...

2019

Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock

Felix Naef, Frédéric Bruno Martin Gachon, Jake Yeung

Mammalian physiology resonates with the daily changes in the external environment, allowing processes such as rest-activity cycles, metabolism, and body temperature to synchronize with daily changes in the surroundings. Studies have identified the molecula ...

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT2018

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Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

National Academy of Sciences2019

Differential Heating Drives Downslope Flows that Accelerate Mixed-LayerWarming in Ice-Covered Waters

Alfred Johny Wüest, Damien Bouffard, Hugo Nicolás Ulloa Sánchez, Kraig Bates Winters

2019

Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock

Felix Naef, Frédéric Bruno Martin Gachon, Jake Yeung

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT2018