Publications related to Metagenomics

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

Bruno Lemaitre, Samuel Rommelaere, Fanny Schüpfer, Florent François Masson, Alice Marra

Insects are frequently infected with heritable bacterial endosymbionts. Endosymbionts have a dramatic impact on their host physiology and evolution. Their tissue distribution is variable with some species being housed intracellularly, some extracellularly ...

2021

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Stewart Cole, Charlotte Avanzi, Philippe Busso

Background Hansen's disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins ...

BMC2021

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Xavier Fernandez-Real Girona

Background Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. Methods We studied gut microbiome composition and ...

BMJ PUBLISHING GROUP2021

Unravelling the collateral damage of antibiotics on gut bacteria

Camille Véronique Bernadette Goemans

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the composition of gut microbiota and causing dysbiosis and disease1. Despite this well-known collateral damage, the activity spectrum of different antibiotic classes on ...

2021

DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies

Nicolas Jean Philippe Guex, Murielle Bochud, Cristian Carmeli, Aurélien Thomas, Tiziana Caputo

As a powerful phenotyping technology, metabolomics provides new opportunities in biomarker discovery through metabolome-wide association studies (MWAS) and the identification of metabolites having a regulatory effect in various biological processes. While ...

2021

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Anders Meibom, Guilhem Maurice Louis Banc-Prandi, Maoz Fine, Romain Savary

Corals from the northern Red Sea and Gulf of Aqaba exhibit extreme thermal tolerance. To examine the underlying gene expression dynamics, we exposed Stylophora pistillata from the Gulf of Aqaba to short-term (hours) and long-term (weeks) heat stress with p ...

2021

Antibiotics-induced monodominance of a novel gut bacterial order

Christoph Merten, Sebastian Martin Waszak

Objective the composition of the healthy human adult gut microbiome is relatively stable over prolonged periods, and representatives of the most highly abundant and prevalent species have been cultured and described. However, microbial abundances can chang ...

2020

Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models

Noushin Hadadi, Vikash Kumar Pandey, Anush Chiappino-Pepe, Merten Morales, Florence Mehl

Understanding the adaptive responses of individual bacterial strains is crucial for microbiome engineering approaches that introduce new functionalities into complex microbiomes, such as xenobiotic compound metabolism for soil bioremediation. Adaptation re ...

NATURE PUBLISHING GROUP2020

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Metagenomics

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Unravelling the collateral damage of antibiotics on gut bacteria

DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Antibiotics-induced monodominance of a novel gut bacterial order

Methylation of arsenic by single-species and soil-derived microbial cultures

Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models

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Chat with Graph Search

DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies

Methylation of arsenic by single-species and soil-derived microbial cultures

Antibiotics-induced monodominance of a novel gut bacterial order

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells

Unravelling the collateral damage of antibiotics on gut bacteria

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models