Concept

Hydrophobe

Related publications (179)

A highly efficient extraction protocol for magnetic particles on a digital microfluidic chip

Martinus Gijs, Matteo Cornaglia, Josias Basil Wacker

We present a novel, simple and highly efficient protocol for the extraction of magnetic particles out of individual droplets on a digital lab-on-chip in the presence of a spatially fixed magnet with a permanent magnetic field. In this approach, the particl ...

Elsevier Science Sa2014

Marangoni induced force on a drop in a Hele Shaw cell

François Gallaire, Philippe Meliga

We analyse the force balance on a cylindrical drop in a Hele-Shaw cell, subjected to a Marangoni flow caused by a surface tension gradient. Depth-averaged Stokes equations, called Brinkman equations, are introduced and a general closed form solution is obt ...

American Institute of Physics2014

On-Chip Fabrication of Paclitaxel-Loaded Chitosan Nanoparticles for Cancer Therapeutics

Philippe Renaud, Arnaud Bertsch, Mohammad Mahdi Hasani-Sadrabadi, Shahin Bonakdar, Fatemeh Sadat Majedi, Jules John Vandersarl

The use of solvent-free microfluidics to fine-tune the physical and chemical properties of chitosan nanoparticles for drug delivery is demonstrated. Nanoparticle self-assembly is driven by pH changes in a water environment, which increases biocompatibility ...

Wiley-Blackwell2014

Mesoscale Characterization of Supramolecular Transient Networks Using SAXS and Rheology

Maartje Martina Cornelia Bastings

Hydrogels and, in particular, supramolecular hydrogels show promising properties for application in regenerative medicine because of their ability to adapt to the natural environment these materials are brought into. However, only few studies focus on the ...

MDPI2014

A structure-guided fragment-based approach for the discovery of allosteric inhibitors targeting the lipophilic binding site of transcription factor EthR

Stewart Cole, Benoit Lechartier

A structure-guided fragment-based approach was used to target the lipophilic allosteric binding site of Mycobacterium tuberculosis EthR. This elongated channel has many hydrophobic residues lining the binding site, with few opportunities for hydrogen bondi ...

Portland Press Ltd2014

Fabrication of a high aspect ratio (HAR) micropillar filter for a magnetic bead-based immunoassay

Martinus Gijs, Christine Ruffert

A microfluidic chip has been realized for investigating immune cell (U937) activation with lipopolysaccharide (LPS) and subsequent pro-inflammatory cytokine (Interleukin-6, IL-6) detection (Ruffert et al. Proc. EMBL Conference Microfluidics 2012a, p 184; P ...

Springer2014

Amphiphilic amino acids: a key to adsorbing proteins to nanopatterned surfaces?

Francesco Stellacci

It has been suggested that amphiphilic amino acids play an important role in the adsorption of proteins on nanostructured surfaces with an ordered, striped domain structure such as those presented by monolayer-protected metal nanoparticles (MPMNs). We have ...

Royal Soc Chemistry2013

Enhancing Hydrophilicity of Anatase TiO2 Surfaces by Deposition of Alkaline Earths: The Case of Ca

Michel Posternak, Alfonso Baldereschi

We show with DFT calculations within the COSMO framework that the wetting energy of clean or hydroxylated anatase TiO2 surfaces is strongly enhanced by Ca deposition at low coverage. Two mechanisms contribute to this behavior: the ionic character of Ca ads ...

Amer Chemical Soc2013

The Fate of a Zwitterion in Water from ab Initio Molecular Dynamics: Monoethanolamine (MEA)-CO2

Wanda Andreoni, Fabio Pietrucci

Understanding the fundamental reactions accompanying the capture of carbon dioxide in amine solutions is critical for the design of high-performance solvents and requires an accurate modeling of the solute-solvent interaction. As a first step toward this g ...

Amer Chemical Soc2013

Stern Layer Formation Induced by Hydrophobic Interactions: A Molecular Level Study

Sylvie Roke, Yixing Chen, Rüdiger Scheu

The molecular ionic surface structure and charge of the electric double layer around a nanodroplet and its structural change induced by hydrophobic effects are measured using vibrational coherent surface scattering spectroscopy, second harmonic scattering, ...

Amer Chemical Soc2013

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