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Product isolation increasingly becomes a major bottleneck in molecular biotechnology. This is especially the case for the sensitive proteineous substances (recombinant proteins, antibodies) and lately also DNA, usually produced in low concentration. The cu ...
The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...
Chromatography is increasingly being used for large-scale preparative separation of precious biological components such as recombinant proteins and DNA. Several kinds of mathematical models are used to describe the liquid chromatography process. The aim of ...
A finite element simulation has been used in order to study the partition chromatography process of one species between an aqueous mobile phase and an organic stationary phase located at the bottom of a rectangular microchannel. The transient model incorpo ...
Research on microfluidic devices for biological analysis has progressed sufficiently to be developed into point-of-care diagnostics products. The goal of this thesis is to improve multiple aspects of capillary-driven microfluidic devices. In particular, th ...
This paper presents a feasibility study on the development of a gas preconcentrator based on micro-reactor technology on silicon. The objectives are to select a gas adsorbent material, to produce a silicon micro-reactor with an integrated heater, and final ...
The isolation and sepn. of the mol. variants of monoclonal IgA from cell culture supernatants is possible using several filtration and ion-exchange chromatog. steps, followed by size-exclusion chromatog. for the actual sepn. of the mol. variants. The latte ...
PAH (N-(4-aminobenzoyl)glycin) clearance measurements have been used for 50 years in clinical research for the determination of renal plasma flow. The quantitation of PAH in plasma or urine is generally performed by colorimetric method after diazotation re ...
This paper describes a lab-on-a-chip device for continuous liquid/solid chromatography measurements. Chromatographic separations of phenolic test solutions as well as of vitamins are illustrating the ability and versatility of the system. The dependence of ...
This paper presents the evaluation of different adsorbents for the improvement of the performances of a gas preconcentrator by targeting the adsorption of a large range of volatiles organics compounds (VOCs) The objectives of this work are to find the adeq ...
