Concept

Autotransfusion

Related publications (13)

In vitro investigations of red blood cell phase separation in a complex microchannel network

Microvascular networks feature a complex topology with multiple bifurcating vessels. Nonuniform partitioning (phase separation) of red blood cells (RBCs) occurs at diverging bifurcations, leading to a heterogeneous RBC distribution that ultimately affects ...

2020

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Nikolaos Stergiopoulos, Olivier Burri, Marc Chambon, Julien Bortoli Chapalay, Fabiana Pereira Da Costa Fraga, Augusto Martins Lima, Maiia Bragina

Despite significant advances in the treatment of cardiovascular diseases, antiplatelet therapies are still associated with a high risk of hemorrhage. In order to develop new drugs, methods to measure platelet function must be adapted for the high-throughpu ...

TAYLOR & FRANCIS INC2019

Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues

Bruno Lemaitre, Elodie Julie Virginie Ramond

The use of adult Drosophila melanogaster as a model for hematopoiesis or organismal immunity has been debated. Addressing this question, we identify an extensive reservoir of blood cells (hemocytes) at the respiratory epithelia (tracheal air sacs) of the t ...

CELL PRESS2019

Flow simulation and hemolysis modeling for a blood centrifuge device

Mark Sawley, Michel Deville, Patric Hagmann

A common blood separation technique is to accelerate the sedimentation of blood constituents by centrifugation and then collect these constituents separately. When subjected to conditions of excessive stress, hemolysis can however occur, whereby the membra ...

Pergamon-Elsevier Science Ltd2013

Purpose Liver cancer is the 5 most common cancer and shows poor prognosis. Surgical removal of liver tumours, the only existing curative treatment, can merely be used in 10-20% of the case. Increasing surgical precision is a key-challenge to give more pati ...

2012

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We present a microfluidic device capable of separating platelets from other blood cells in continuous flow using dielectrophoresis field-flow-fractionation. The use of hydrodynamic focusing in combination with the application of a dielectrophoretic force a ...

American Institute of Physics2011

Chronic wound healing by fetal cell therapy may be explained by differential gene profiling observed in fetal versus old skin cells

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri

Engineering of fetal tissue has a high potential for the treatment of acute and chronic wounds of the skin in humans as these cells have high expansion capacity under simple culture conditions and one organ donation can produce Master Cell Banks which can ...

2009

Whole-cell bioprocessing of human fetal cells for tissue engineering of skin

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity (simple culture conditions), maintenance of differentiated phenotype for primary human cell culture and trans ...

2009

In vivo evaluation of human fetal cells as allogenic cell source for tissue engineering

Dominique Pioletti, Pierre-Etienne Bourban, Corinne Scaletta

The aim of this study was to test the association of fetal bone cells with ceramic reinforced PLA scaffolds for tissue engineering. As animal models, the craniotomy and the femoral condyle approaches in rats were chosen to follow cortical and trabecular bo ...

2008

Consistency of fetal cell banks for research and clinical use

Dominique Pioletti, Corinne Scaletta, Aurélie Quintin

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity and maintenance of differentiated phenotype for primary human cell culture. In our experience, we have seen t ...

2007

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