Concept

Organic synthesis

Related publications (340)

Synthesis and characterization of constrained cyclosporin A derivatives containing a pseudo-proline group

The chemical synthesis, conformational analysis and receptor binding studies of novel constrained cyclosporin A (CsA) analogues are described. The selective insertion of pseudo-proline (PsiPro) systems featuring different 2-C-substituents at the oxazolidin ...

2003

Modelling the fate of oxidisable organic contaminants in groundwater

David Andrew Barry

Subsurface contamination by organic chemicals is a pervasive environmental problem, susceptible to remediation by natural or enhanced attenuation approaches or more highly engineered methods such as pump-and-treat, amongst others. Such remediation approach ...

Elsevier Science B. V.2003

Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: New leads as selective beta-galactosidase inhibitors

Pierre Vogel, Inmaculada Robina, Raynald Demange

The preparation of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives in a stereoselective route starting from D-glucose and ethyl acetoacetate is presented. Ethyl ester (6), N,N-diethylamide (7) and N-isopropylamide (8) have been tested towards 25 ...

2002

Modelling the fate of oxidisable organic contaminants in groundwater

David Andrew Barry

2002

Highly enantio- and diastereoselective inverse electron demand hetero-Diels-Alder reaction

Karl Gademann

A highly enantioselective and diastereoselective inverse electron demand hetero-Diels-Alder reaction between a variety of alpha,beta-unsatd. aldehydes and Et vinyl ether is described. The reaction is catalyzed by a chiral tridentate chromium(III) Schiff ba ...

2002

Synthesis of organometallics and catalytic hydrogenations in ionic liquids

Paul Joseph Dyson

New solvents provide synthetic chemists with the opportunity of conducting new reactions and carrying out new processes. In this paper the author's own work on organometallic chemistry in ionic liquids is reviewed and placed in context with studies from ot ...

2002

Stereoselective synthesis of new 8-oxabicyclo[3.2.1]oct-6-en-2-one and 8-oxabicyclo[3.2.1]octa-3,6-dien-2-one derivatives. The electron-releasing and electron-withdrawing effects of homoconjugated ketones

Pierre Vogel

Two successive brominations of 8-oxabicyclo[3.2.1]oct-6-en-2-one 6 provided 3-exo,6-exo,7-endo-tribromo-7oxabicyclo[3.2.1]octan-2-endo-one 10 with high stereoselectivity. NaBH4 reduced 10 into 3-exo, 6-exo,7-endo-tribromo-8-oxabicyclo[3.2.1]octan-2-endo-ol ...

2001

Towards a total synthesis of aminoacylated t-RNAs

In the ribosomal biosynthesis of proteins, the aminoacylated t-RNAs serve as carriers of the amino acids. A total synthesis of these biol. key-compds. would allow the site-specific incorporation of modifications within the t-RNA and attachment of any desir ...

2001

Primary or secondary electrochemical generator

Michael Graetzel

A high power density and high capacity primary or secondary electrochemical generator in which at least one electrode (1,2) is composed of an electrically active solid material, said electrode having a mesoporous texture forming a bicontinuous junction of ...

2001

Multi-layer microfluidic glass chips for microanalytical applications

Nico de Rooij, Rolf Wüthrich, Valia Fascio

A new, versatile architecture is presented for microfluidic devices made entirely from glass, for use with reagents which would prove highly corrosive for silicon. Chips consist of three layers of glass wafers bonded together by fusion bonding. On the insi ...

2001

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.