Concept

Molecular phylogenetics

Related publications (152)

Malaria: targeting parasite and host cell kinomes

Malaria still remains one of the deadliest infectious diseases, and has a tremendous morbidity and mortality impact in the developing world. The propensity of the parasites to develop drug resistance, and the relative reluctance of the pharmaceutical indus ...

2010

Visual backward masking deficits in schizophrenic patients are associated with polymorphisms in the nicotinic receptor α7 subunit gene (CHRNA7)

Michael Herzog, Maya Roinishvili

Visual backward masking (BM) deficits are often proposed to be trait markers for schizophrenia revealing the genetic underpinnings of the disease. Here, we show that, indeed, masking deficits in the shine-through effect are associated with polymorphisms in ...

2010

Self-Assembly of Nanoporous Chiral Networks with Varying Symmetry from Sexiphenyl-dicarbonitrile on Ag(111)

Harald Brune, Uta Schlickum, Régis Decker

The self-assembly of sexiphenyl-dicarbonitrile molecules on the Ag(111) surface is investigated using low-temperature scanning tunneling microscopy (STM) in ultrahigh vacuum. Several nanoporous networks with varying symmetry and pore size coexist on the su ...

American Chemical Society2009

Maximum independent sets of commuting and noninterfering inversions

Bernard Moret, Krister Swenson

Background: Given three signed permutations, an inversion median is a fourth permutation that minimizes the sum of the pairwise inversion distances between it and the three others. This problem is NP-hard as well as hard to approximate. Yet median-based ap ...

2009

Time-resolved x-ray absorption spectroscopy: Watching atoms dance

Majed Chergui, Paul Beaud, Wojciech Gawelda, Camelia Borca, Van Thai Pham, Amal El Nahhas, Renske Marjan van der Veen, Frederico Alves Lima

The introduction of pump-probe techniques to the field of x-ray absorption spectroscopy (XAS) has allowed the monitoring of both structural and electronic dynamics of disordered systems in the condensed phase with unprecedented accuracy, both in time and i ...

Iop Publishing Ltd, Dirac House, Temple Back, Bristol Bs1 6Be, England2009

Improving inference of transcriptional regulatory networks based on network evolutionary models

Bernard Moret, Xiuwei Zhang

Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present evolutionary approaches to improve the inference of regulatory networks for a family of ...

Springer2009

Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition

Didier Trono, Priscilla Turelli, Bastien Mangeat, Olivier Michielin

Retroelements are important evolutionary forces but can be deleterious if left uncontrolled. Members of the human APOBEC3 family of cytidine deaminases can inhibit a wide range of endogenous, as well as exogenous, retroelements. These enzymes are structura ...

2009

Structural Aspects of 1,3,5-Benzenetrisamides−A New Family of Nucleating Agents

Philip Pattison

Structural studies of substituted 1,3,5-benzenetrisamides, a new family of highly versatile and efficient nucleating and clarifying agents for polymeric materials, are reported. Subtle details of the molecular structure of these species are shown to have a ...

2009

All-optical runaway evaporation to Bose-Einstein condensation

Jean-Philippe Brantut

We demonstrate runaway evaporative cooling directly with a tightly confining optical-dipole trap and achieve fast production of condensates of 1.5×105 87Rb atoms. Our scheme uses a misaligned crossed-beam far off-resonance optical-dipole trap (MACRO-FORT). ...

American Physical Society2009

DCJ median problems on linear multichromosomal genomes: Graph representation and fast exact solutions

Wei Xu

Given a set of genomes g and a distance measure d, the genome rearrangement median problem asks for another genome q that minimizes Sigma n is an element of g(d(q,g)). This problem lies at the heart of phylogenetic reconstruction from rearrangement data. w ...

Springer2009

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