Concept

X-inactivation

Related publications (57)

Mycobacterium tuberculosis: drug-resistance mechanisms

Tuberculosis has resurged during the past decade in many industrialized countries, and strains of Mycobacterium tuberculosis that are resistant to one or more of the main antituberculous drugs are emerging. The molecular basis of mycobacterial drug resista ...

1994

Maternal inheritance of P cytotype in Drosophila melanogaster: a "pre-P cytotype" is strictly extra-chromosomally transmitted

Bruno Lemaitre

In Drosophila melanogaster, transposition of the P element is under the control of a cellular state known as cytotype. The P cytotype represses P transposition whereas the M cytotype is permissive for transposition. In the long-term, the P cytotype is dete ...

1993

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

Thierry Laroche

DNA fragments containing the silencers that flank the mating type genes at HML alpha are shown to bind specifically to the nuclear scaffold of yeast. The scaffold proteins are solubilized with urea and then renatured to form a soluble extract which allows ...

1989

Chromosome segregation at meiosis I in female T(2;4)1Go/+ mice: no evidence for a decreased crossover frequency with maternal age

Friedrich Beermann

The influence of age and hormones on chromosome segregation at meiosis I was studied in female mice heterozygous for the T(2;4)1Go translocation. Females of two age groups (18-22 and 40-56 weeks old) were stimulated for ovulation with different doses of go ...

1987

Long term cultivation of Namalva cells for interferon production: stable cytogenetic markers for identification of cells in spite of drastic chromosomal variation

Florian Maria Wurm

Namalva cells were propagated continuously over a period of up to 18 months. During this period the chromosomal status of the cell populations were investigated cytogenetically. The ability of the cells to produce interferons after induction with Sendai vi ...

1985

A fine analysis of glucose-phosphate-isomerase patterns in single preimplantation mouse embryos

Denis Duboule

Mouse embryos were derived from eggs heterozygous for alleles of the dimeric enzyme glucose phosphate isomerase (Gpi-1a/Gpi-1b) that had been fertilized with sperm carrying a third allele (Gpi-1c). This particular combination makes it possible to study the ...

1985

N-Acetoxy-acetylaminofluorene reacts preferentially with a control region of intracellular SV40 chromosome

Peter Martin Beard

Many chemical carcinogens or their metabolites react with DNA; thus it is of interest to determine what effect chromosomal structure has on these reactions. The chromosome of simian virus 40 (SV40) is well suited for such studies; like chromatin of eukaryo ...

1981

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